5308-63-4

Usage

Uses

Used in Pharmaceutical Industry:
1-(5-METHYL-PYRIDIN-2-YL)-ETHANONE is used as a chemical intermediate for the synthesis of pharmaceuticals due to its reactivity with multiple reagents, enabling the creation of a wide range of derivative compounds for medicinal applications.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 1-(5-METHYL-PYRIDIN-2-YL)-ETHANONE serves as an intermediate in the production of various agrochemicals, contributing to the development of substances for agricultural and pest control purposes.
Used in Fragrance and Flavoring Industry:
1-(5-METHYL-PYRIDIN-2-YL)-ETHANONE is also utilized in the fragrance and flavoring industry, capitalizing on its ability to contribute to the formation of distinct scents and tastes in consumer products.
Safety Considerations:

InChI:InChI=1/C8H9NO/c1-6-4-3-5-9-8(6)7(2)10/h3-5H,1-2H3

Upstream product

• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 127-19-5 N,N-dimethyl acetamide 
• 1122-72-1 6-methyl-2-pyridinecarboxaldehyde 
• 71777-66-7 (+/-)-1-[2-(6-methylpyridyl)]ethanol 
• 18113-81-0 2-ethyl-5-methylpyridine 
• 1620-77-5 5-methylpicolinonitrile 
• 75-16-1 methylmagnesium bromide 
• 3510-66-5 2-Bromo-5-methylpyridine 
• 85279-27-2 1-(6-methyl-2-piperidyl)ethan-1-ol 
• 74-88-4 methyl iodide 

Downstream Products

• 1429939-70-7 C₂₁H₁₉F₄N₅O 
• 1429939-77-4 C₂₁H₂₀F₃N₅O 
• 1429939-91-2 C₁₀H₉F₂NO₂ 

Relevant academic research and scientific papers

A highly rigid ditopic conjugate with orthogonal coordination axes and its zinc(II) and copper(II) complexes

A highly rigid ditopic ligand has been prepared which consists of a terpy fragment connected in the back to a phen nucleus via a 1,4-phenylene linker. The chemical structure of the presently reported ligand is such that the coordination axes of the two ch

Nanoscale Metal–Organic Layers for Deeply Penetrating X-ray-Induced Photodynamic Therapy

We report the rational design of metal–organic layers (MOLs) that are built from [Hf6O4(OH)4(HCO2)6] secondary building units (SBUs) and Ir[bpy(ppy)2]+- or [Ru(bpy)3]

Quantitative Sensitization Efficiencies in NIR-Emissive Homoleptic Ln(III) Complexes Using 2-(5-Methylpyridin-2-yl)-8-hydroxyquinoline

A series of isostructural lanthanide complexes [Ln(MPQ)3] (Ln = Nd, Gd, Er, Yb, Lu) using a monoanionic tridentate methylpyridyl-substituted 8-hydroxyquinoline ligand (MPHQ = 2-(5-methylpyridin-2-yl)-8-hydroxyquinoline) have been prepared and c

Metal Templated Receptors for the Effective Complexation of Dicarboxylates

In this paper we show that a thiourea-functionalized terpyridine unit can be induced to form, in the presence of ruthenium(II), a well-ordered recognition site for dicarboxylate ions.Strong binding to the self-assembled receptor can be followed by 1H NMR in DMSO and association constants of >104 M-1 were measured in certain cases.

A mesoporous NNN-pincer-based metal-organic framework scaffold for the preparation of noble-metal-free catalysts

Through topology-guided synthesis, a Zr-based mesoporous MOF was successfully constructed, adopting a β-cristobalite-type structure. The MOF is embedded with well-arranged terpyridine coordination sites for facile post-synthetic metalation, and can be effectively used as a general scaffold for the preparation of noble-metal-free catalysts. For instance, the scaffolded metal@MOF material exhibits highly efficient catalytic activity for alkene epoxidation and arene borylation.

NANOSCALE METAL-ORGANIC LAYERS AND METAL-ORGANIC NANOPLATES FOR X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, RODIODYNAMIC THERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF

Metal-organic layers (MOLs) and metal-organic nanoplates (MOPs) comprising photosensitizers are described. The MOLs and MOPs can also include moieties capable of absorbing X-rays or other ionizing irradiation energy and/or scintillation. Optionally, the p

Self-Supporting Metal-Organic Layers as Single-Site Solid Catalysts

Metal-organic layers (MOLs) represent an emerging class of tunable and functionalizable two-dimensional materials. In this work, the scalable solvothermal synthesis of self-supporting MOLs composed of [Hf6O4(OH)4(HCO2

N ortho acyl substituted nitrogen-containing heterocyclic compound and process for preparing aminal iron (II) complexes thereof

Provided are a process for preparing an N ortho acyl substituted nitrogen-containing heterocyclic compound and an aminal iron (II) complex thereof, and the use of the complexes obtained by the process in an olefin oligomerization catalyst. The N ortho acyl substituted nitrogen-containing heterocyclic compound in the present invention is for example 2-acyl-1,10-phenanthroline or 2,6-diacetyl pyridine as shown in formula b, and the N ortho acyl substituted nitrogen-containing heterocyclic compound in the present invention is produced by a reaction of a precursor thereof in a substituted or unsubstituted nitrobenzene. Preferably the precursor shown in formula I in the present invention is produced by 1,10-phenanthroline reacting with trialkyl aluminum, or a halogenoalkyl aluminum RnAIXm, or a substituted or unsubstituted benzyl lithium Ph′CH2Li, followed by hydrolysis. The preparation method provided in the present invention has a few synthetic steps, an easy process, a low toxic effect, and reduces the preparation costs of the catalyst, and has a promising outlook in the industrial application.

NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF

There is provided a morpholine derivative represented by General Formula [1A] or a salt thereof. (In the formula, a ring A represents a ring represented by General Formula [I]; * represents a bonding position; Z2 represents CH or the like; Z1 represents CR6 or the like; R6 represents a hydrogen atom or the like; X1 represents CHR7 or the like; R7 represents a hydrogen atom or the like; X2 represents CH2 or the like; R1 and R2 are the same as or different from each other, and each of R1 and R2 represents a hydrogen atom or the like; R3, R4, and R5 are the same as or different from each other, and each of R3, R4, and R5 represents a hydrogen atom, NRaRb, or the like; and each of Ra and Rb represents a hydrogen atom, a C1-8 alkyl group which may have a substituent, or the like.)

Effects of structural modifications on the metal binding, anti-amyloid activity, and cholinesterase inhibitory activity of chalcones

As the number of individuals affected with Alzheimer's disease (AD) increases and the availability of drugs for AD treatment remains limited, the need to develop effective therapeutics for AD becomes more and more pressing. Strategies currently pursued include inhibiting acetylcholinesterase (AChE) and targeting amyloid-β (Aβ) peptides and metal-Aβ complexes. This work presents the design, synthesis, and biochemical evaluation of a series of chalcones, and assesses the relationship between their structures and their ability to bind metal ions and/or Aβ species, and inhibit AChE/BChE activity. Several chalcones were found to exhibit potent disaggregation of pre-formed N-biotinyl Aβ1-42 (bioAβ42) aggregates in vitro in the absence and presence of Cu2+/Zn2+, while others were effective at inhibiting the action of AChE.