53088-69-0

Basic information

• Product Name: METHYL 3-METHYLPHENYLACETATE
• Synonyms: METHYL 3-METHYLPHENYLACETATE;METHYL M-TOLYLACETATE;Methyl 3-methylphenylacetate,98%;Methyl 3-Methylphenylacetate, 98% 5GR;Methyl 2-(M-tolyl)acetate
• CAS NO: 53088-69-0
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2
• Mol File: 53088-69-0.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 117 °C (13 mmHg)
• Flash Point: 99.8°C
• Appearance: Clear colorless to slightly yellow/Liquid
• Density: 1.035g/cm³
• Vapor Pressure: 0.0798mmHg at 25°C
• Refractive Index: 1.5045-1.5065
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL 3-METHYLPHENYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-METHYLPHENYLACETATE(53088-69-0)
• EPA Substance Registry System: METHYL 3-METHYLPHENYLACETATE(53088-69-0)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 53088-69-0(Hazardous Substances Data)

Usage

Chemical Properties

clear colorless to slightly yellow liquid

InChI:InChI=1/C10H12O2/c1-8-4-3-5-9(6-8)7-10(11)12-2/h3-6H,7H2,1-2H3

Upstream product

• 620-13-3 1-bromomethyl-3-methyl-benzene 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 39180-84-2 N-methyl-1-(m-tolyl)methanamine 
• 621-36-3 m-methylphenylacetic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 2947-60-6 3-methylbenzyl cyanide 
• 126889-61-0 4-methylbenzocyclobuten-1(2H)-one 
• 124-41-4 sodium methylate 
• 20667-76-9 3-methyl-1-p-tolyltriazene 
• 186581-53-3 diazomethane 

Downstream Products

• 384365-48-4 methyl 3-methylphenyldiazoacetate 
• 1875-89-4 2-(3-methylphenyl)ethanol 
• 141879-56-3 ethyl N-(diphenylmethylene)-3-<(carbomethoxy)methyl>-DL-phenylalaninate 
• 141879-45-0 2-Amino-3-(3-carboxymethyl-phenyl)-propionic acid 
• 175169-67-2 (15S)-16-m-tolyl-17,18,19,20-tetranorisocarbacyclin methylester 
• 175275-99-7 (15R)-16-m-tolyl-17,18,19,20-tetranorisocarbacyclin methylester 
• 175169-69-4 5-{(1R,2R,3S,5R,6R,7R)-2-Iodo-6-[(E)-(S)-4-m-tolyl-3-((R)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyloxy)-but-1-enyl]-9-oxa-tricyclo[3.3.1.0^3,7]non-1-yl}-pentanoic acid methyl ester 
• 175169-66-1 5-[(3aS,5R,6R,6aS)-5-Hydroxy-6-((E)-3-oxo-4-m-tolyl-but-1-enyl)-1,3a,4,5,6,6a-hexahydro-pentalen-2-yl]-pentanoic acid methyl ester 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF A CHIRAL PROSTAGLANDIN ENOL INTERMEDIATE AND INTERMEDIATE COMPOUNDS USEFUL IN THE PROCESS

The present invention relates to a process for the preparation of a chiral prostaglandin enol intermediate of formula 1, comprising the steps of: separating a compound of formula 16-(R,S)-10 into its diastereomers by fractional crystallisation, reducing t

Pd-Catalyzed Decarboxylative Olefination: Stereoselective Synthesis of Polysubstituted Butadienes and Macrocyclic P-glycoprotein Inhibitors

The efficient and stereoselective synthesis of polysubstituted butadienes, especially the multifunctional butadienes, represents a great challenge in organic synthesis. Herein, we wish to report a distinctive Pd(0) carbene-initiated decarboxylative olefination approach that enables the direct coupling of diazo esters with vinylethylene carbonates (VECs), vinyl oxazolidinones, or vinyl benzoxazinones to afford alcohol-, amine-, or aniline-containing 1,3-dienes in moderate to high yields and with excellent stereoselectivity. This protocol features operational simplicity, mild reaction conditions, a broad substrate scope, and gram-scalability. Notably, a structurally unique allylic Pd(II) intermediate was isolated and characterized. DFT calculation and control experiments demonstrated that a rare Pd(0) carbene intermediate could be involved in this reaction. Moreover, the polysubstituted butadienes as novel building blocks were unprecedentedly assembled into macrocycles, which efficiently inhibited the P-glycoprotein and dramatically reversed multidrug resistance in cancer cells by 190-fold.

Pyrimidine onium compound and application thereof

The invention relates to a pyrimidine onium compound, nitride oxides, salt of the nitride oxides and a composition comprising the compound. The invention further relates to an application of the compound to plant pest control.