5310-51-0

Usage

Uses

Used in the Food Industry:
(E)-3-[3-[(E)-2-carboxyethenyl]phenyl]prop-2-enoic acid is used as a natural preservative and flavor enhancer in the food industry. Its antioxidant properties help in extending the shelf life of various food products by neutralizing harmful free radicals and preventing oxidation.
Used in the Cosmetic Industry:
In the cosmetic industry, (E)-3-[3-[(E)-2-carboxyethenyl]phenyl]prop-2-enoic acid is utilized as an ingredient in anti-aging and skin-protective products. Its antioxidant and anti-inflammatory properties contribute to the maintenance of healthy skin and the reduction of visible signs of aging.
Used in the Pharmaceutical Industry:
(E)-3-[3-[(E)-2-carboxyethenyl]phenyl]prop-2-enoic acid is employed in the pharmaceutical industry for its potential health benefits, particularly in the development of treatments aimed at reducing the risk of cardiovascular disease and cancer. Its antioxidant and anti-inflammatory properties make it a promising candidate for therapeutic applications.
Overall, (E)-3-[3-[(E)-2-carboxyethenyl]phenyl]prop-2-enoic acid is a versatile and significant chemical compound with a wide range of potential applications across various industries, as well as offering numerous health benefits.

Upstream product

• 186581-53-3 diazomethane 
• 1084-76-0 DNP-Gly 
• 5680-79-5 glycine ethyl ester hydrochloride 
• 70-34-8 2,4-Dinitrofluorobenzene 
• 89-02-1 2,4-dinitrobenzenesulfonic acid 
• 616-34-2 methoxycarbonylmethylamine 
• 584-48-5 2,4-dinitrobromobenzene 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 67-56-1 methanol 

Downstream Products

• 93-84-5 5-nitro-2,3-dihydro-1H-benzimidazol-2-one 
• 1084-76-0 DNP-Gly 

Relevant academic research and scientific papers

Synthesis of o-Nitroarylamines via Ipso Nucleophilic Substitution of Sulfonic Acids

A mild, efficient, and eco-friendly method for the synthesis of o-nitroarylamine from o-nitroaryl sulfonic acid via ipso nucleophilic aryl substitution by amine is described. The products have been obtained with good yields at room temperature without the assistance of any metal, activating agent, or toxic oxidant. This method is useful for racemization-free synthesis of N-aryl amino acid esters.

A general approach for the development of fluorogenic probes suitable for no-wash imaging of kinases in live cells

A general approach is presented for developing small molecule-based fluorogenic probes suitable for no-wash imaging of endogenous kinases in live cells. Probe 1, including a fluorophore-quencher system, was only turned on upon reacting with its target kinase Btk, and disclosed Btk's cellular location in live cells without any washing.

Transcription factor modulating compounds and methods of use thereof

Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.

Transcription factor modulating compounds and methods of use thereof

Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.

REACTIONS OF METHYL ESTERS OF N-(2,4-DINITROPHENYL)GLYCINE AND N-METHYL-N-(2,4-DINITROPHENYL)GLYCINE WITH SODIUM METHOXIDE

The reaction of methyl ester of N-(2,4-dinitrophenyl)glycine (I) with sodium methoxide produces 5-nitro-2(3H)benzimidazolone (III).The product identity has been proved by its isolation from the reaction mixture under conditions similar to those of kinetic experiments and by independent synthesis.The reaction of methyl ester of N-methyl-N-(2,4-dinitrophenyl)glycine with methoxide proceeds in two steps, the second one being substantially slower.The first step produces N-methyl-2-nitroso-4-nitroaniline (IV), which can be prepared by this reaction in good yield andpurity.N-Methyl-2-nitroso-4-nitroaniline undergoes subsequent reactions in the methoxide solutions.Products of the subsequent reactions have not been identified at the starting ester II concentrations of about 10-4 mol l-1, whereas at higher concentrations of the starting substance the reaction produces 2-amino-2'-methylamino-5,5'-dinitro-ONN-azoxybenzene (V) and 2,2'-bis(methylamino)-5,5'-dinitroazoxybenzene (VI).