53112-33-7 Usage
Uses
Used in Pharmaceutical Research:
N-METHYL-1,2,3,4-TETRAHYDROISOQUINOL-INE HYDROCHLORIDE is used as a pharmacological tool for studying dopamine receptors, aiding in the understanding of their role in various neurological conditions.
Used in Parkinson's Disease Treatment:
N-METHYL-1,2,3,4-TETRAHYDROISOQUINOL-INE HYDROCHLORIDE is used as a potential treatment for Parkinson's disease, due to its effects on dopamine receptors and its potential to alleviate symptoms associated with the condition.
Used in Substance Abuse Disorders:
N-METHYL-1,2,3,4-TETRAHYDROISOQUINOL-INE HYDROCHLORIDE is used as a potential anti-addictive agent for substance abuse disorders, given its ability to modulate dopamine uptake and impact the central nervous system.
Used in Neuroscience and Drug Discovery:
N-METHYL-1,2,3,4-TETRAHYDROISOQUINOL-INE HYDROCHLORIDE is used as a promising candidate for further research and development in the field of neuroscience and drug discovery, due to its psychoactive properties and potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 53112-33-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,1,1 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 53112-33:
(7*5)+(6*3)+(5*1)+(4*1)+(3*2)+(2*3)+(1*3)=77
77 % 10 = 7
So 53112-33-7 is a valid CAS Registry Number.
53112-33-7Relevant academic research and scientific papers
Frustrated Lewis Pair Catalyzed Hydrogenation of Amides: Halides as Active Lewis Base in the Metal-Free Hydrogen Activation
Sitte, Nikolai A.,Bursch, Markus,Grimme, Stefan,Paradies, Jan
, p. 159 - 162 (2019/01/04)
A method for the metal-free reduction of carboxylic amides using oxalyl chloride as an activating agent and hydrogen as the final reductant is introduced. The reaction proceeds via the hydrogen splitting by B(2,6-F2-C6H3)3 in combination with chloride as the Lewis base. Density functional theory calculations support the unprecedented role of halides as active Lewis base components in the frustrated Lewis pair mediated hydrogen activation. The reaction displays broad substrate scope for tertiary benzoic acid amides and α-branched carboxamides.
N-Methylation of Amines with Methanol at Room Temperature
Tsarev, Vasily N.,Morioka, Yuna,Caner, Joaquim,Wang, Qing,Ushimaru, Richiro,Kudo, Akihiko,Naka, Hiroshi,Saito, Susumu
supporting information, p. 2530 - 2533 (2015/05/27)
N-Methylation of amines with methanol proceeds at room temperature in the presence of a silver-loaded titanium dioxide (Ag/TiO2) photocatalyst under UV-vis light irradiation. This method allows facile synthesis/isolation of N-methylamines bearing various functional groups including N-benzyl, N-allyl, N-Boc, hydroxyl, ether, acetal, carboxamide, formamide, and olefin groups. (Chemical Presented)
