53164-84-4Relevant academic research and scientific papers
Effects of π-extension on pyrrole hemithioindigo photoswitches
Zweig, Joshua E.,Ko, Tongil A.,Huang, Junrou,Newhouse, Timothy R.
, (2019)
The most red-shifted hemithioindigo photoswitches have been identified through systematic introduction of aryl units to a parent pyrrole hemithioindigo photoswitch. Increasing the size of the 5′-aryl substituent is ineffective at producing further redshif
Total Synthesis of the Marine Alkaloid Discoipyrrole C via the MoOPH-Mediated Oxidation of a 2,3,5-Trisubstituted Pyrrole
Yan, Qiao,Ma, Xiang,Banwell, Martin G.,Ward, Jas S.
, p. 3305 - 3313 (2018/01/02)
A total synthesis of the marine alkaloid discoipyrrole C (3) is described. In the pivotal step, the 2,3,5-trisubstituted pyrrole 19 was treated with MoOPH in the presence of MeOH, and the resulting methoxylated 1,2-dihydro-3H-pyrrol-3-one 20 subjected to reaction with potassium carbonate in MeOH then trifluoroacetic acid and H2O. This gave a mixture of target 3 and its dehydration product, and the structure of the former compound was confirmed by single-crystal X-ray analysis.
Modular Total Syntheses of the Alkaloids Discoipyrroles A and B, Potent Inhibitors of the DDR2 Signaling Pathway
Zhang, Yiwen,Banwell, Martin G.,Carr, Paul D.,Willis, Anthony C.
supporting information, p. 704 - 707 (2016/03/01)
(Chemical Equation Presented). The title natural product 1 has been synthesized by treating the 1,2,3,5-tetrasubstituted pyrrole 23 with oxoperoxymolybdenum(pyridine) (hexamethylphosphoric triamide) (MoOPH). Compound 23 was itself prepared in seven steps
Antiinflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their corresponding sulfoxides and sulfones
-
, (2008/06/13)
Antiinflammatory 4,5-diaryl-2-(substituted-thio)pyrroles and their corresponding sulfoxides and sulfones, useful for treating arthritis and related diseases.
