532412-73-0

Upstream product

• 124-38-9 carbon dioxide 
• 532412-74-1 {2-[2-bromo-6-(3-methylbut-2-enyl)phenylsulfanyl]ethyl}trimethylsilane 
• 608-30-0 2,6-dibromoaniline 
• 532412-71-8 [2-(2,6-dibromophenylsulfanyl)ethyl]trimethylsilane 
• 18143-30-1 2-trimethylsilylethanethiol 

Downstream Products

• 945594-30-9 3-(3-methylbut-2-enyl)-2-[2-(trimethylsilanyl)-ethanesulfanyl]-benzoic acid p-nitrophenyl ester 
• 945594-26-3 3-(3-methylbut-2-enyl)-2-[2-(trimethylsilanyl)-ethanesulfanyl]-benzoic acid S-phenyl ester 
• 945594-31-0 3-(3-methylbut-2-enyl)-2-[2-(trimethylsilanyl)-ethanesulfanyl]-benzoic acid phenyl ester 
• 945594-32-1 3-(3-methylbut-2-enyl)-2-[2-(trimethylsilanyl)-ethanesulfanyl]-benzoic acid methyl ester 
• 1035808-32-2 3-(3-methylbut-2-enyl)-2-[2-(trimethylsilanyl)ethylsulfanyl]thiobenzoic acid S-[2-(trimethylsilanyl)ethyl]ester 
• 945594-33-2 3-(3-methylbut-2-enyl)-2-[2-(trimethylsilanyl)-ethanesulfinyl]-benzoic acid p-nitrophenyl ester 
• 945594-27-4 3-(3-methylbut-2-enyl)-2-[2-(trimethylsilanyl)-ethanesulfinyl]-benzoic acid S-phenyl ester 
• 945594-35-4 3-(3-methylbut-2-enyl)-2-[2-(trimethylsilanyl)-ethanesulfinyl]-benzoic acid methyl ester 
• 945594-34-3 3-(3-methylbut-2-enyl)-2-[2-(trimethylsilanyl)-ethanesulfinyl]-benzoic acid phenyl ester 

Relevant academic research and scientific papers

Small molecules that mimic the thiol-triggered alkylating properties seen in the natural product leinamycin

Reaction of the antitumor agent leinamycin with cellular thiols results in conversion of the natural product to a DNA-alkylating episulfonium alkylating agent via an intriguing sequence of chemical reactions. To establish whether the chemistry first seen