5325-89-3Relevant articles and documents
Design, synthesis, docking and biological evaluation of chalcones as promising antidiabetic agents
Bhaskar, Baki Vijaya,Gu, Wei,Rammohan, Aluru,Venkateswarlu, Nagam,Zyryanov, Grigory V.
, (2020/01/08)
Diabetes mellitus (DM) is a serious chronic metabolic disorder which occurs due to dysfunction of insulin and therapeutic approaches are poor. It is an under estimation that 387 million people currently suffering globally with diabetic and more than 592 m
Design, synthesis, molecular modeling, and ADMET studies of some pyrazoline derivatives as shikimate kinase inhibitors
James, Jainey P.,Ishwar Bhat,More, Uttam A.,Joshi, Shrinivas D.
, p. 546 - 559 (2017/11/16)
A series of pyrazoline derivatives were synthesized and their structures have been characterized by IR, 1H NMR, 13C NMR, mass spectral and elemental analysis. The novel compounds were designed as Mycobacterium tuberculosis shikimate
In vitro antioxidant activity and scavenging effects of some synthesized 4-Aminochalcones
Prasad, Y.Rajendra,Rani, V. Jhansi,Rao, A. Srinivasa
, p. 52 - 58 (2013/02/22)
A new series of substituted 4'-aminochalcones were synthesized by Claisen-Schmidt condensation of 4-aminoacetophenone with various substituted aromatic/heteroaromatic aldehydes. The antioxidant activity for all these compounds were studied on various reac