5326-93-2

Usage

Physical State

Colorless to pale yellow liquid

Odor

Strong

Uses

Corrosion inhibitor, industrial biocide, production of adhesives, sealants, and rubber products

Health Hazards

Potent irritant to skin, eyes, and respiratory system; exposure to high concentrations can cause nausea, vomiting, and central nervous system depression

Environmental Persistence

Low solubility in water, known to persist in the environment, potentially posing a risk to aquatic organisms

Safety Precautions

Proper handling and safety precautions are necessary when working with 2,2-Dichloro-N,N-bis(1-methylethyl)acetamide.

InChI:InChI=1/C8H15Cl2NO/c1-5(2)11(6(3)4)8(12)7(9)10/h5-7H,1-4H3

Upstream product

• 79-36-7 dichloroacethyl chloride 
• 108-18-9 diisopropylamine 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 
• 96-79-7 (2-chloroethyl)-diisopropylamine 

Downstream Products

• 59832-10-9 (E)-N,N-diisopropyl-3-(4-methoxyphenyl)acrylamide 

Relevant academic research and scientific papers

Transformations of N-ethylamines into amide derivatives under the action of sulfur monochloride

Tertiary N-ethylamines were converted into amide derivatives by reactions with sulfur monochloride and DABCO at 0 °C. Depending on the nature of the substituents in the amine, the reaction can be accompanied by unexpected transformations.

Sequential reactions promoted by manganese: Completely stereoselective synthesis of (E)-α,β-unsaturated amides, ketones, aldehydes, and carboxylic acids

(Chemical Equation Presented) A complete E-selective synthesis of α,β-unsaturated amides through a sequential reaction of a range of dichloroamides with a variety of aldehydes promoted by Rieke manganese (Mn*) is reported. A mechanism based on a sequential aldol-type reaction and a completely stereoselective β-elimination is proposed to explain these results. The unsaturated amides obtained are readily and efficiently transformed into α,β-unsaturated ketones, aldehydes, or carboxylic acids without loss of the diastereoisomeric purity of the C-C double bond.

Direct conversion of N-ethylamines into functionalised amides by S2Cl2

Hünig's base 1 is known to react extensively with S2Cl2 to give monocyclic, bicyclic and fused tricyclic 1,2-dithioles with the N-ethyl group intact, but with S2Cl2 and DABCO in chloroform at 0 °C 1 is converted

Method of protecting corn from herbicides

Corn is protected from S-alkyl thiocarbamate herbicides, while obtaining good control of unwanted plant species by applying to the soil in the vicinity of corn seed an effective but non-phytotoxic amount of an N,N-diisopropyl, N-benzyl-N-methyl, N-benzyl-N-ethyl, N-(p-methoxybenzyl), N-methyl-N-phenethyl or N,N-diethyl amide of dichloroacetic, dibromoacetic or tribromoacetic acids.