5327-72-0 Usage
General Description
1,4-diaminoanthracene-9,10-diol is a chemical compound with the molecular formula C14H12N2O2. It is a derivative of anthracene and contains two amino groups and two hydroxyl groups. 1,4-diaminoanthracene-9,10-diol is used in organic synthesis, as a building block for various chemical reactions. It can also be used as a precursor for the production of dyes and pigments. In addition, 1,4-diaminoanthracene-9,10-diol has potential applications in the field of medicine, particularly in cancer research, due to its ability to interact with DNA and potentially inhibit the growth of cancer cells. However, like many chemical compounds, it also poses potential health risks and should be handled with caution in laboratory and industrial settings.
Check Digit Verification of cas no
The CAS Registry Mumber 5327-72-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,2 and 7 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5327-72:
(6*5)+(5*3)+(4*2)+(3*7)+(2*7)+(1*2)=90
90 % 10 = 0
So 5327-72-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H12N2O2/c15-9-5-6-10(16)12-11(9)13(17)7-3-1-2-4-8(7)14(12)18/h1-6,17-18H,15-16H2
5327-72-0Relevant articles and documents
Synthesis and antiproliferative activity of 1,4-bis(dimethylamino)-9,10- anthraquinone derivatives against P388 mouse leukemic tumor cells
Jin, Guang-Zhu,Jin, Hai-Shan,Jin, Li-Li
experimental part, p. 1071 - 1076 (2012/07/27)
A series of 2-substituted-1,4-bis(dimethylamino)-9,10-anthraquinone derivatives were synthesized and their in vitro antiproliferative activities against p388 mouse leukemic tumor cells were evaluated. In addition, the effect of substituents on the phenyl ring was investigated. Among the derivatives tested, seven showed a high antiproliferative effect and three showed a moderate effect. In addition, introduction of a series of substituted phenyl groups into 1,4-bis(dimethylamino)-9,10-anthraquinone at 2-position were shown to enhance its antiproliferative activity. The antiproliferative activity also increased upon substitution of the benzene ring by an electron donating group such as an amine or methoxyl group.
