53277-42-2

Basic information

• Product Name: 1H-Pyrrolo[2,3-b]pyridine, 1-acetyl- (9CI)
• Synonyms: 1H-Pyrrolo[2,3-b]pyridine, 1-acetyl- (9CI);1H-Pyrrolo[2,3-b]pyridine, 1-acetyl-;1-(1H-pyrrolo[2,3-b]pyridin-1-yl)ethanone
• CAS NO: 53277-42-2
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.17262
• Product Categories: ACETYLGROUP
• Mol File: 53277-42-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 63-65 °C
• Boiling Point: 275.0±13.0 °C(Predicted)
• Appearance: /
• Density: 1.21±0.1 g/cm3(Predicted)
• PKA: 2.76±0.30(Predicted)
• CAS DataBase Reference: 1H-Pyrrolo[2,3-b]pyridine, 1-acetyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrolo[2,3-b]pyridine, 1-acetyl- (9CI)(53277-42-2)
• EPA Substance Registry System: 1H-Pyrrolo[2,3-b]pyridine, 1-acetyl- (9CI)(53277-42-2)

Safety Data

• Hazardous Substances Data: 53277-42-2(Hazardous Substances Data)

Usage

Classification

Organic compound

Compound Class

Pyrrolopyridines

Structural Feature

Pyrrolopyridine skeleton with a ketone group at position 1

Potential Applications

Pharmaceuticals, agrochemicals

Usage

Building block in the synthesis of biologically active compounds

Medicinal Properties

Under investigation for potential benefits

Research Status

Further research needed to fully understand and harness its potential benefits

Upstream product

• 271-63-6 7-Azaindole 
• 127-19-5 N,N-dimethyl acetamide 
• 108-24-7 acetic anhydride 
• 108-05-4 vinyl acetate 

Downstream Products

• 60884-14-2 7-acetyl-2,2-diphenyl-2,2a,7,7a-tetrahydro-oxeto[3',2':4,5]pyrrolo[2,3-b]pyridine 
• 111097-45-1 1-acetyl-2,3-dihydropyrrolo<2,3-b>pyridine 
• 5654-95-5 1H-pyrrolo[2,3-b]pyridine-2,3-dione 
• 271-63-6 7-Azaindole 

Relevant articles and documents

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Oxidant-controlled regioselectivity in the oxidative arylation of N-acetylindoles

N-Acetylindoles can be oxidatively coupled with arenes such as benzene or pentafluorobenzene in dioxane. The use of Cu(OAc)2 as the stoichiometric oxidant produces selective arylation at the 3-position of indole while AgOAc produces selective a

Reactivity of 1H-Pyrrolopyridine. I. Synthesis of 3-Acetyl-7-azaindole and Related Compounds

The bihaviour of 1H-pyrrolo(2,3-b)pyridine (7-azaindole) towards several acylating reagents are reported.The preparation of 3-acetyl-7-azaindole, 3-chloroacetyl-7-azaindole and 3-(2-hydroxyethyl)-7-azaindole are described.