53277-47-7

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 4-chloro-6-methylnicotinate is used as an intermediate in the synthesis of various drugs for its contribution to the development of pharmaceuticals with potential therapeutic applications.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, Methyl 4-chloro-6-methylnicotinate is utilized as an intermediate in the production of agrochemicals, playing a role in the creation of substances that can enhance crop protection and yield.
Used as a Flavoring Agent in Food and Beverage Industry:
Beyond its applications in synthesis, Methyl 4-chloro-6-methylnicotinate is also employed as a flavoring agent in the food and beverage industry, adding a distinct taste to various products.
Safety Precautions:
It is crucial to handle Methyl 4-chloro-6-methylnicotinate with care due to its potential harmful effects if swallowed, inhaled, or comes into contact with the skin, emphasizing the need for proper safety measures during its use and production.

InChI:InChI=1/C8H8ClNO2/c1-5-3-7(9)6(4-10-5)8(11)12-2/h3-4H,1-2H3

Upstream product

• 67-56-1 methanol 
• 39853-81-1 2-chloro-6-methyl-nicotinic acid chloride 
• 30529-70-5 2-chloro-6-methyl nicotinic acid 
• 68-12-2 N,N-dimethyl-formamide 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 79-37-8 oxalyl dichloride 
• 74-88-4 methyl iodide 

Downstream Products

• 232602-13-0 2-benzyl-6-methyl-nicotinic acid methyl ester 
• 223761-04-4 methyl 2-(4-fluorophenyl)-6-methylpyridin-3-carboxylate 
• 31686-93-8 methyl 2-amino-6-methylnicotinate 
• 76336-15-7 1,2-dihydro-4-hydroxy-7-methyl-2-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester 
• 69407-72-3 1,7-dimethyl-1,2-dihydro-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxylic acid ethyl ester 
• 1312697-17-8 5-[5-(3,5-Bistrifluoromethylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-indolizine-8-carboxylic acid [(2,2,2-trifluoroethylcarbamoyl)methyl]-amide 
• 1312697-60-1 5-[5-(3,5-bistrifluoromethylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-indolizine-8-carboxylic acid 
• 1312697-63-4 6-[5-(3,5-bistrifluoromethylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-chloro-nicotinic acid methyl ester 
• 1312697-64-5 6-[5-(3,5-bistrifluoromethylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-prop-1-ynyl-nicotinic acid methyl ester 
• 1312697-65-6 5-[5-(3,5-bis-trifluoromethylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-indolizine-8-carboxylic acid methyl ester 
• 1312697-77-0 5-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-1,3-dimethylindolizine-8-carboxylic acid 
• 1312697-78-1 2-chloro-6-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-nicotinic acid methyl ester 
• 1312697-79-2 6-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-(3-hydroxy-but-1-ynyl)-nicotinic acid methyl ester 
• 1312697-80-5 6-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-(3-methanesulfonyloxy-but-1-ynyl)-nicotinic acid methyl ester 

Relevant academic research and scientific papers

BENZO[B][1,8]NAPHTHYRIDINE ACETIC ACID DERIVATIVES AND METHODS OF USE

Compounds of Formula I or pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formula I as effective modulators of STING are also provided.

COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION

The invention provides compounds of the formula (I): (I) wherein A1, A2, R2, R4, B1, B2, X, X1, n, a and b are as defined are defined in the specification, to pharmaceutical comp

PYRIDINE COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORS

The present disclosure is directed to inhibitors of SHP2 and their use in the treatment of disease. Also disclosed are pharmaceutical compositions comprising the same.

SPIROCYCLIC COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS

The present invention is directed to spirocyclic compounds which are inhibitors of tryptophan hydroxylase (TPH), particularly isoform 1 (TPH1), that are useful in the treatment of diseases or disorders associated with peripheral serotonin including, for example, gastrointestinal, cardiovascular, pulmonary, inflammatory, metabolic, and low bone mass diseases, as well as serotonin syndrome, and cancer.

2-HYDROXYMETHYL-SUBSTITUTED OREXIN RECEPTOR ANTAGONISTS

The present invention is directed to 2-hydroxymethyl compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

THIOARYL DERIVATIVES AS GPR120 AGONISTS

The present invention relates to thioaryl derivatives of Formula 1 as defined in the specification, a method for preparing the same, a pharmaceutical composition comprising the same and use thereof. The thioaryl derivatives of Formula 1 according to the present invention promote GLP-1 formation in the gastrointestinal tract and improve insulin resistance in macrophages, pancreas cells, etc. due to anti-inflammatory action, and can accordingly be effectively used for preventing or treating diabetes, complications of diabetes, inflammation, obesity, non-alcoholic fatty liver, steatohepatitis or osteoporosis.

ANTIPARISITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME

The present invention relates to novel dihydroazole of formula (I) and salts thereof: Wherein R1, A1, A2, G, X and Y are as defined in the description, compositions thereof, processes for their preparation and their uses t

ANTI PARASITIC DIHYDROAZOLE COMPOUNDS AND COMPOSITIONS COMPRISING SAME

The present invention relates to novel dihydroazole of formula (I) and salts thereof: Wherein R1, A1, A2, G, X and Y are as defined in the description, compositions thereof, processes for their preparation and their uses t

NOVEL COMPOUNDS

Disclosed are N-{[(1R,4S,6R)-3-(2-pyridinylcarbonyl)-3-azabicyclo[4.1.0]hept-4-yl]methyl}-2-heteroarylamine derivatives and their use as pharmaceuticals.

PIPERIDINE DERIVATIVES USEFUL AS OREXIN ANTAGONISTS

This invention relates to imidazopyridylmethylene substituted piperidine derivatives orexin antagonists and their use as pharmaceuticals.