532940-99-1Relevant academic research and scientific papers
Catalytic alkynylation of ketones and aldehydes using quaternary ammonium hydroxide base
Ishikawa, Teruhiko,Mizuta, Tomohiro,Hagiwara, Kumiko,Aikawa, Toshiaki,Kudo, Takayuki,Saito, Seiki
, p. 3702 - 3705 (2003)
Catalytic alkynylation of diverse ketones and aldehydes using nonmetallic benzyltrimethylammonium hydroxide or a basic resin of the hydroxide type in DMSO is described. Aliphatic or alicyclic carbonyl partners gave satisfactory results, whereas aromatic o
Stereoselective synthesis of (2 Z,4 E)-2,4-pentadien-1-ols via sequential 1,4-elimination reaction and [1,2]-wittig rearrangement starting from (E)-4-alkoxy-2-butenyl benzoates
Nakano, Takeo,Soeta, Takahiro,Endo, Kohei,Inomata, Katsuhiko,Ukaji, Yutaka
, p. 12654 - 12661 (2014/01/17)
The sequential 1,4-elimination reaction of (E)-4-alkoxy-2-butenyl benzoates and [1,2]-Wittig rearrangement gave (2Z,4E)-2,4-pentadien-1-ols stereoselectively. Z-Selective formation of intermediary vinyl ethers, whose stereochemistry was well elucidated by the "syn-effect", was achieved by treatment of the 2-butenyl benzoates with KOH in the presence of Pd catalyst. The subsequent [1,2]-Wittg rearrangement by use of n-BuLi proceeded with retention of the stereochemistry of the intermediary vinyl ethers.
Diastereoselective zinco-cyclopropanation of chiral allylic alcohols with gem-dizinc carbenoids
Fournier, Jean-Francois,Mathieu, Simon,Charette, Andre B.
, p. 13140 - 13141 (2007/10/03)
The highly diastereoselective zinco-cyclopropanation of chiral allylic alcohols using gem-dizinc carbenoids is described. The reaction produces three contiguous stereogenic centers, and the resulting chiral cyclopropylzinc derivatives can be trapped with
Iron carbonyl-mediated homologous Michael reactions of γ-alkoxy alkenones
Zhou,Green
, p. 4497 - 4500 (2007/10/02)
Iron tetracarbonyl complexes of γ-benzyloxy-α,β-unsaturated ketones react with several nucleophiles in the presence of Lewis acids to give γ-substitution products. The allyltetracarbonyliron cation intermediates generated allow retention of configuration of the double bond.
