533-06-2 Usage
Originator
Tolseram,Squibb,US,1954
Manufacturing Process
A solution of 32 g (0.30 mol) phosgene in 200 ml benzene is added dropwise at 30°C to a stirred solution of 53.5 g (0.32 mol) 3-o-toloxy-1,2-propanediol in 400 ml benzene. The mixture is stirred for an hour after the addition is completed, and a solution of 39 g of dimethylaniline in 100 ml benzene is then added, and stirring continued for a half-hour. Ice water (about one-third volume) is then added, and the benzene layer formed is separated and stirred with 500 mi concentrated ammonia at 5°C for six hours. The precipitated solid (weighing about 55 g) is recovered and recrystallized from water. The product thus obtained in a yield of about 53 g is 3-(o-toloxy)-2-hydroxypropyl carbamate: it is a crystalline solid melting at about 93°C, and having a lower water-solubility and higher oil-solubility than 3-o-toloxy-1,2-propanediol.
Therapeutic Function
Muscle relaxant
Synthesis Reference(s)
Journal of the American Chemical Society, 72, p. 3710, 1950 DOI: 10.1021/ja01164a107
Check Digit Verification of cas no
The CAS Registry Mumber 533-06-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,3 and 3 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 533-06:
(5*5)+(4*3)+(3*3)+(2*0)+(1*6)=52
52 % 10 = 2
So 533-06-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H15NO4/c1-8-4-2-3-5-10(8)15-6-9(13)7-16-11(12)14/h2-5,9,13H,6-7H2,1H3,(H2,12,14)
