5335-91-1Relevant academic research and scientific papers
Reactions of ethylidene diacetate: Formation of N-vinylamide precursors ethylidene bisacetamide and ethylidene bisformamide
Rabasco, John J.,Waller, Francis J.
, p. 4953 - 4956 (2007/10/03)
Ethylidene diacetate (EDA) reacts with formamide or acetamide under stoichiometric base or catalytic Lewis acid conditions to afford the corresponding ethylidene bisamides and N-vinylamides. Sn(OAc)2 afforded an overall 82.6% selectivity to the desired acetamide derivatives. Sn(OAc)2 and Zn(OAc)2 facilitate amide attack at the tertiary carbon of EDA.
The Synthesis of 1-Aminoalkylphosphonic Acids. A Revised Mechanism of the Reaction of Phosphorus Trichloride, Amides and Aldehydes or Ketones in Acetic Acid (Oleksyszyn Reaction)
Soroka, Miroslaw
, p. 331 - 334 (2007/10/02)
The mechanism of the amidoalkylation of trivalent phosphorus compounds in acetic acid has been reinvestigated.Evidence is presented that 1-(acylamino)alkyl acetates 5 and not N,N'-alkylidenebisamides 2 are the intermediates in this reaction.Supporting literature analogies are discussed.This paper also describes a convenient procedure for the preparation of crude (acylamino)alkyl alkanoates 5, which are excellent amidoalkylating agents.The usefulness of these reagents is demonstrated by a simple two-step "one pot" synthesis of 1-aminoalkylphosphinic acids 1.
REACTION OF THE AMIDES OF MONOCARBOXYLIC ACIDS WITH VINYL ALKYL ETHERS AND THE STRUCTURE OF THE ADDITION PRODUCTS
Voronkov, M. G.,Keiko, N. A.,Kuznetsova, T. A.,Frolov, Yu. L.,Kalikhman, I. D.,Chuvashev, Yu. A.
, p. 1738 - 1741 (2007/10/02)
The reaction of vinyl alkyl ethers with the amides of monocarboxylic acids leads to the formation of 1,1-di(acylamino)ethanes.
