53355-55-8 Usage
Reactive reagent
Used in organic synthesis for the preparation of pyrazole derivatives 1H-Pyrazole-1-carbonyl chloride is a reactive chemical compound, commonly used in the synthesis of various pyrazole derivatives.
Versatile building block
In the pharmaceutical industry 1H-Pyrazole-1-carbonyl chloride is a versatile building block in the pharmaceutical industry, making it useful for the development of drug molecules.
Potential applications
Development of drug molecules Due to its ability to modify the structure and properties of organic compounds, 1H-Pyrazole-1-carbonyl chloride has potential applications in the development of new drug molecules.
High reactivity
Towards nucleophiles 1H-Pyrazole-1-carbonyl chloride is known for its high reactivity towards nucleophiles, making it a popular choice in synthetic chemistry.
Introduction of pyrazole functional group
Into a variety of compounds 1H-Pyrazole-1-carbonyl chloride is often used in synthetic chemistry for the introduction of the pyrazole functional group into numerous compounds.
Handling and safety
Use with caution, in accordance with proper safety procedures Due to its reactivity, 1H-Pyrazole-1-carbonyl chloride should be handled and used with caution, following appropriate safety guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 53355-55-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,3,5 and 5 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 53355-55:
(7*5)+(6*3)+(5*3)+(4*5)+(3*5)+(2*5)+(1*5)=118
118 % 10 = 8
So 53355-55-8 is a valid CAS Registry Number.
53355-55-8Relevant academic research and scientific papers
N-Acyl pyrazoles: Effective and tunable inhibitors of serine hydrolases
Otrubova, Katerina,Chatterjee, Shreyosree,Ghimire, Srijana,Cravatt, Benjamin F.,Boger, Dale L.
, p. 1693 - 1703 (2019/03/21)
A series of N-acyl pyrazoles was examined as candidate serine hydrolase inhibitors in which the active site acylating reactivity and the leaving group ability of the pyrazole could be tuned not only through the nature of the acyl group (reactivity: amide
Discovery libraries targeting the major enzyme classes: The serine hydrolases
Otrubova, Katerina,Srinivasan, Venkat,Boger, Dale L.
supporting information, p. 3807 - 3813 (2014/09/16)
Two libraries of modestly reactive ureas containing either electron-deficient acyl anilines or acyl pyrazoles were prepared and are reported as screening libraries for candidate serine hydrolase inhibitors. Within each library is a small but powerful subs
