53388-86-6

Basic information

• Product Name: 5-BroMo-3,3-diMethylindoline
• Synonyms: 5-BroMo-3,3-diMethylindoline;5-Bromo-3,3-dimethyl-2,3-dihydro-1H-indole
• CAS NO: 53388-86-6
• Molecular Formula: C₁₀H₁₂BrN
• Molecular Weight: 226.11298
• Mol File: 53388-86-6.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 5-BroMo-3,3-diMethylindoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BroMo-3,3-diMethylindoline(53388-86-6)
• EPA Substance Registry System: 5-BroMo-3,3-diMethylindoline(53388-86-6)

Safety Data

• Hazardous Substances Data: 53388-86-6(Hazardous Substances Data)

Upstream product

• 78-84-2 isobutyraldehyde 
• 589-21-9 (4-bromophenyl)hydrazine 
• 16940-66-2 sodium tetrahydroborate 
• 622-88-8 4-bromophenylhydrazine hydrochloride 
• 866364-70-7 1-(5-bromo-3,3-dimethylindolin-1-yl)ethan-1-one 
• 16078-32-3 1-(3,3-dimethylindolin-1-yl)ethan-1-one 
• 1914-02-9 3,3-dimethylindoline 
• 19155-24-9 3,3-dimethyloxindole 
• 120902-45-6 5-bromo-3,3-dimethyl-1,3-dihydro-2H-indol-2-one 
• 6310-21-0 2-(1,1-dimethylethyl)-benzenamine 
• 850012-44-1 4-bromo-(2-tert-butyl)aniline 
• 1373751-89-3 1-azido-4-bromo-2-tert-butylbenzene 

Downstream Products

• 645417-03-4 ethyl {4-[(5-bromo-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]-2-methylphenoxy}acetate 
• 1613147-59-3 (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(3,3-dimethyl-2,3-dihydro-1H-indol-5-yl)pyridin-2-amine 
• 844901-54-8 5-Bromo-3,3-dimethyl-1-(4-nitrophenylsulphonyl)-2,3-dihydro-1H-indole 

Relevant articles and documents

LIPOXYGENASE INHIBITORS

Various embodiments of the present disclosure are directed to compounds having Formula (I), Formula (IA), Formula (IB), Formula (IC), Formula (ID), Formula (IE), and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases, and/or treating associated diseases, such as Alzheimer's disease. In some embodiments, the compounds may be administered to a patient as part of a pharmaceutical formulation.

Iron-Catalyzed Intramolecular Aminations of C(sp3)?H Bonds in Alkylaryl Azides

The nucleophilic iron complex Bu4N[Fe(CO)3(NO)] (TBA[Fe]) catalyzes the direct intramolecular amination of unactivated C(sp3)?H bonds in alkylaryl azides, which results in the formation of substituted indoline and tetrahydroquinoline derivatives.

4,5,6,7-TETRAHYDRO-1 H-PYRAZOLO[4,3-C]PYRIDIN-3-AMINE COMPOUNDS AS CBP AND/OR EP300 INHIBITORS

The present invention relates to compounds of formula (I) or formula (II): and to salts thereof, wherein R1-R4 of formula (I) and R1-R3 of formula (II) have any of the values defined herein, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) of formula (II) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.