5343-69-1Relevant academic research and scientific papers
One-pot synthesis of salicylanilides by direct amide bond formation from salicyclic acid under microwave irradiation
Lu, Cheng-Rong,Zhao, Bei,Jiang, Ying-Peng,Ding, Hao,Yang, Sheng
experimental part, p. 1257 - 1266 (2011/05/07)
A highly efficient protocol for the preparation of aromatic amides is described by the direct reactions between salicyclic acid and aromatic amines in the presence of phosphorous trichloride under microwave irradiation. The method has several advantages over the conventional methods, including operational simplicity, good yield, and reduced reaction time.
BORON TRICHLORIDE CATALYZED ORTHO CARBONYLATION OF PHENOLS: SYNTHESIS OF 2-HYDROXY-ARYL-CARBOXYAMIDES AND -KETONES.
Piccolo, Oreste,Filippini, Lucio,Tinucci, Laura,Valoti, Ermanno,Citterio, Attilio
, p. 885 - 892 (2007/10/02)
In the presence of equimolar quantity of BCl3, phenols 1 react with isocyanates and acyl chlorides to give, usually with good-excellent yields, 2-hydroxy-aryl-carboxy-amides 2 and 2-hydroxy-aryl-ketones 3 respectively.A distinctive behaviour of BCl3 in comparison with other Lewis acids is observed.
