53432-81-8Relevant articles and documents
Samarium(II) iodide-promoted intermolecular and intramolecular ketone- nitrile reductive coupling reactions
Zhou, Longhu,Zhang, Yongmin,Shi, Daqing
, p. 91 - 98 (2007/10/03)
Samarium (II) iodide, a strong one-electron transfer reducing reagent, has been successfully utilized for the intermolecular and intramolecular reductive coupling reactions of ketones with nitriles, α-Hydroxy ketones, monocyclic, fused bicyclic α-hydroxy ketones and monocyclic α-amino alcohols composed of a number of substitution patterns have been prepared in good yields at room temperature or reflux under neutral conditions. The procedure can avoid overreduction of the resulting of α-hydroxy ketones or α-amino alcohols. The crystal structures of monocyclic α-amino alcohols are reported.