5346-73-6

Basic information

• Product Name: 1-O,3-O,4-O,6-O-Tetramethyl-β-D-fructofuranosyl 2-O,3-O,4-O,6-O-tetramethyl-α-D-glucopyranoside
• Synonyms: 1-O,3-O,4-O,6-O-Tetramethyl-β-D-fructofuranosyl 2-O,3-O,4-O,6-O-tetramethyl-α-D-glucopyranoside;Octa-O-methylsucrose
• CAS NO: 5346-73-6
• Molecular Formula: C13H9BrINO
• Molecular Weight: 454.51
• Mol File: 5346-73-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 498.9°C at 760 mmHg
• Flash Point: 192.4°C
• Appearance: /
• Density: 1.15g/cm³
• Vapor Pressure: 1.34E-09mmHg at 25°C
• Refractive Index: 1.471
• CAS DataBase Reference: 1-O,3-O,4-O,6-O-Tetramethyl-β-D-fructofuranosyl 2-O,3-O,4-O,6-O-tetramethyl-α-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O,3-O,4-O,6-O-Tetramethyl-β-D-fructofuranosyl 2-O,3-O,4-O,6-O-tetramethyl-α-D-glucopyranoside(5346-73-6)
• EPA Substance Registry System: 1-O,3-O,4-O,6-O-Tetramethyl-β-D-fructofuranosyl 2-O,3-O,4-O,6-O-tetramethyl-α-D-glucopyranoside(5346-73-6)

Safety Data

• Hazardous Substances Data: 5346-73-6(Hazardous Substances Data)

Usage

Chemical composition

Consists of a fructofuranosyl and a glucopyranoside component.

Fructofuranosyl linkage

Attached to the 2-O, 3-O, 4-O, and 6-O positions of the glucose component.

Glucopyranoside component

Contains additional methyl groups at various positions.

Methyl groups

Both fructofuranosyl and glucopyranoside components have multiple methyl groups.

Molecular structure

A complex carbohydrate derivative.

Potential applications

Utilized in chemistry, biochemistry, and pharmaceutical research.

Unique properties

The compound possesses a distinctive structure and properties due to its complex composition.

InChI:InChI=1/C20H38O11/c1-21-9-12-14(24-4)16(26-6)17(27-7)19(29-12)31-20(11-23-3)18(28-8)15(25-5)13(30-20)10-22-2/h12-19H,9-11H2,1-8H3

Upstream product

• 77-78-1 dimethyl sulfate 
• 57-50-1 Sucrose 
• 74-88-4 methyl iodide 
• 74-83-9 methyl bromide 
• 126-14-7 sucrose octaacetate 
• 77910-05-5 4'-O-methylsucrose 
• 40437-08-9 2,3,4,6-tetra-O-acetyl-D-glucose 
• 27641-20-9 octa-O-acetyl-isosucrose 
• 124-41-4 sodium methylate 

Relevant articles and documents

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Identification of fungal trehalose for the diagnosis of invasive candidiasis by mass spectrometry

The rapidity of the diagnosis of invasive candidiasis (IC) is crucial to allow the early introduction of antifungal therapy that dramatically increases the survival rate of patients. Early diagnosis is unfortunately often delayed because Candida blood culture, the gold standard diagnostic test, is positive in only 50% of cases of IC and takes several days to obtain this result. Complementary non-culture-based methods relying on the detection of Candida cell wall polysaccharides in the serum, β-glucans and mannans, by enzymatic and immunological reagents have been successfully developed to allow a more efficient patients care. We have previously demonstrated that detection of circulating glycans by mass spectrometry could provide a reliable and cost-effective early diagnosis method called MS-DS for Mass Spectrometry of Di-Saccharide. Here, by comparing patient's sera and Candida albicans strains deficient in carbohydrates synthesis, we demonstrate that trehalose derived from fungal metabolism can be specifically targeted by MS-DS to allow early diagnosis. In particular, the use of C. albicans strains deficient in the synthesis of trehalose synthesizing enzymes Tps1 and Tps2 show that MS-DS results were correlated to the metabolism of trehalose. Finally, we demonstrate that the performance of the IC diagnosis can be significantly improved by using high resolution mass spectrometry, which opens new perspectives in the management of the disease.

Peralkylation of Saccharides under Aqueous Conditions

Treatment of saccharides with sodium hydroxide and alkyl halides in aqueous dimethyl sulfoxide solution offers a very efficient method for the complete alkylation of saccharides in high yields.