53473-85-1

Usage

Uses

Used in Disinfectants and Biocides:
1,2-Benzisothiazol-5-amine(9CI) is used as an active ingredient in disinfectants and biocides for its potent antimicrobial properties. It helps in eliminating a broad spectrum of microorganisms, including bacteria, fungi, and viruses, thereby ensuring cleanliness and preventing the spread of infections in various settings.
Used in Pharmaceutical Development:
1,2-Benzisothiazol-5-amine(9CI) is utilized as a key component in the development of pharmaceuticals, particularly drugs with antimicrobial and antifungal properties. Its unique chemical structure allows for the creation of novel therapeutic agents that can combat resistant strains of pathogens and improve treatment outcomes for various infections.
Used in Industrial Chemistry:
In the field of industrial chemistry, 1,2-Benzisothiazol-5-amine(9CI) serves as a valuable intermediate in the synthesis of various chemical compounds and materials. Its reactivity and stability make it suitable for use in the production of dyes, pigments, and other specialty chemicals that require specific properties for their applications.
Used in Research Applications:
1,2-Benzisothiazol-5-amine(9CI) is also employed in research settings for studying its potential applications and understanding its mechanisms of action. Researchers explore its interactions with biological systems, its effects on microorganisms, and its potential synergistic or antagonistic effects when combined with other compounds, thereby expanding the knowledge base and driving innovation in related fields.

InChI:InChI=1/C7H6N2S/c8-6-1-2-7-5(3-6)4-9-10-7/h1-4H,8H2

Upstream product

• 27996-87-8 2-fluoro-5-nitrobenzaldehye 
• 60768-66-3 5-nitro-1,2-benzisothiazole 
• 66882-70-0 isothiazole-4,5-dicarboxylic acid 

Downstream Products

• 66882-70-0 isothiazole-4,5-dicarboxylic acid 
• 75608-07-0 5-hydroxy-1,2-benzisothiazole 

Relevant academic research and scientific papers

HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF

Described herein are compounds, including pharmaceutically acceptable salts thereof, methods of making such compounds, pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat, prevent or diagnose blood-based diseases, disorders or conditions.

9-AZABICYCLO [3 . 3 . 1] NONANE DERIVATIVES AS MONOAMINE REUPTAKE INHIBITORS

The present invention relates to a 9-azabicyclo[3.3.1]nonane derivative of formula (I), wherein R1 is H or C1-5alkyl; X is O or NR2, wherein R2 is H, C1-5alkyl or C2-5acyl and Ar is C6-10aryl or a 5-10 membered heteroaryl ring system, both being optionally substituted with one to three of R3-R5 independently selected from halogen, C1-5alkyl, C1-5alkoxy, C3-6cycloalkyl, C2-5alkenyl, C2-5alkynyl, CN, NO2, hydroxy, phenyl, phenoxy and phenylC1-2alkoxy, wherein said C1-5alkyl and C1-5alkoxy are optionally substituted with one to three halogens and wherein said phenyl, phenoxy and phenylC1-2alkoxy are optionally substituted with one to three substituents independently selected from halogen and methyl or two of R3-R5 at adjacent positions together form a methylenedioxy or propylene unit, with the proviso that the compounds exo-9-methyl-3-phenoxy-9-azabicyclo[3.3.1]nonane and N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-1H indazole-5-amine are excluded, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to pharmaceutical compositions comprising said 9-azabicyclo[3.3.1]nonane derivatives and to their use in therapy.

9-Azabicyclo[3.3.1]nonane derivatives

The present invention relates to a 9-azabicyclo[3.3.1]nonane derivative of formula I, wherein each of the substituents is given the definition as set forth in the specification and claims, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to pharmaceutical compositions comprising said 9-azabicyclo[3.3.1]nonane derivatives and to their use in therapy.

PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS FROM CARBAMATE COMPOUNDS

An improved process for the preparation of 6-(perfluoroalkyl)uracil compounds having structural formula (I) from carbamate compounds having structural formula (II).