53544-22-2
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Basic information
- Product Name: 1,2,6,7-tetrahydrocamptothecin
- Synonyms:
- CAS NO:53544-22-2
- Molecular Formula:
- Molecular Weight: 352.39
- EINECS: N/A
- Product Categories: N/A
- Mol File: 53544-22-2.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 1,2,6,7-tetrahydrocamptothecin(CAS DataBase Reference)
- NIST Chemistry Reference: 1,2,6,7-tetrahydrocamptothecin(53544-22-2)
- EPA Substance Registry System: 1,2,6,7-tetrahydrocamptothecin(53544-22-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 53544-22-2(Hazardous Substances Data)
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53544-22-2 Usage
Chemical origin
Derived from the camptothecin alkaloid, a natural compound found in the Camptotheca acuminata tree.Potency
Potent topoisomerase inhibitor, meaning it has a strong ability to interfere with the action of topoisomerase enzymes.Mechanism of action
Interferes with topoisomerase enzymes, which are essential for DNA replication and transcription, leading to DNA damage and ultimately cell death.Anticancer properties
Promising candidate for anticancer therapy due to its ability to inhibit topoisomerase enzymes and induce cell death.Other therapeutic potential
Has been shown to have potential in the treatment of diseases such as HIV and autoimmune disorders.Chemical structure
Complex chemical structure, which contributes to its potency and therapeutic potential.Synthesis
Synthesis often involves multiple steps, making it a valuable but challenging compound to manufacture for medical research and applications.Research focus
Due to its potential as an anticancer agent and its complex synthesis, 1,2,6,7-tetrahydrocamptothecin is a subject of ongoing research in the fields of medicinal chemistry and pharmacology.Check Digit Verification of cas no
The CAS Registry Mumber 53544-22-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,5,4 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.Calculate Digit Verification of CAS Registry Number 53544-22:
(7*5)+(6*3)+(5*5)+(4*4)+(3*4)+(2*2)+(1*2)=112
112 % 10 = 2
So 53544-22-2 is a valid CAS Registry Number.
53544-22-2Upstream product
53544-22-2Downstream Products
- 19685-09-7 (S)-10-hydroxycamptothecin
- 19685-11-1 (S)-9-acetoxy-4-ethyl-4-hydroxy-1,12-dihydro-4H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione
- 7689-03-4 camptothecin
- 86639-62-5 10-nitro-(20S)-camptothecin
- 68426-53-9 11-hydroxycamptothecin
- 86639-63-6 10-amino-20(S)-camptothecin
- 86639-48-7 Camptothecin 1-oxide
- 19685-10-0 10-methoxycamptothecin
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1,2,6,7-tetrahydrocamptothecin
