53566-38-4

Usage

Uses

Used in Organic Synthesis:
TRIBUTYL[3-(TRIFLUOROMETHYL)PHENYL]STANNANE is used as a reagent in the preparation of various organotin derivatives, contributing to the advancement of organic chemistry and the development of new compounds with potential applications in various fields.
Used in Marine Coatings (Historic Use):
TRIBUTYL[3-(TRIFLUOROMETHYL)PHENYL]STANNANE was historically used as a component in antifouling paints for marine vessels to prevent the growth of marine organisms on the hulls, thereby reducing drag and improving fuel efficiency. However, due to its environmental and health concerns, its use in this application has been restricted or banned in many countries.

InChI:InChI=1/C7H4F3.3C4H9.Sn/c8-7(9,10)6-4-2-1-3-5-6;3*1-3-4-2;/h1-2,4-5H;3*1,3-4H2,2H3;/rC19H31F3Sn/c1-4-7-13-23(14-8-5-2,15-9-6-3)18-12-10-11-17(16-18)19(20,21)22/h10-12,16H,4-9,13-15H2,1-3H3

Upstream product

• 401-78-5 3-bromo-1-trifluoromethylbenzene 
• 1461-22-9 tributyltin chloride 
• 98-17-9 3-Trifluoromethylphenol 
• 1075754-37-8 meta-trifluoromethylphenyl pivalate 
• 17955-46-3 trimethylsilyltributyltin 
• 813-19-4 bis(tri-n-butyltin) 

Downstream Products

• 92622-65-6 1-(3-(trifluoromethyl)benzoyl)-4-tert-butylcyclohex-1-ene 
• 1083330-10-2 dicarbonylcyclopentadienyl(m-trifluoromethylphenyl)iron 
• 1256278-83-7 1-(1-(4-chlorophenyl)-2,2-difluorovinyl)-3-(trifluoromethyl)benzene 
• 1392840-02-6 1-benzyl-5-hydroxy-2-oxo-3-(3-trifluoromethyl-phenyl)-1,2-dihydro-[1,7]naphthyridine-6-carboxylic acid methyl ester 
• 728-81-4 3-(trifluoromethyl)benzophenone 
• 5957-84-6 2-(3-trifluoromethylphenyl)pyridine 

Relevant academic research and scientific papers

Stannylation of Aryl Halides, Stille Cross-Coupling, and One-Pot, Two-Step Stannylation/Stille Cross-Coupling Reactions under Solvent-Free Conditions

Solvent-free protocols for palladium-catalyzed stannylation of aryl halides, Stille cross-coupling, and one-pot, two-step stannylation/Stille cross-coupling (SSC) are reported for the first time. (Het)aryl halides bearing acceptor, donor, as well as sterically demanding substituents are stannylated and/or coupled in high yields. The reactions are catalyzed by conventional palladium(II) acetate/PCy3 [Pd(OAc)2/PCy3] under air, using available base CsF, and without the use of high purity reagents. The developed synthetic procedures are versatile, robust, and easily scalable. The absence of solvent, and the elimination of isolation procedures of aryl stannanes makes the SSC protocol simple, step economical, and highly efficient for the synthesis of biaryls in a one-pot two-step procedure.

Ni-Catalyzed Stannylation of Aryl Esters via C?O Bond Cleavage

A Ni-catalyzed stannylation of aryl esters with air- and moisture-insensitive silylstannyl reagents via Csp2 ?O cleavage is described. This protocol is characterized by its wide scope, including challenging combinations, thus enabling access to versatile building blocks and orthogonal C?heteroatom bond formations.

Pyrazolecarboxylic acid tricyclic derivatives, preparation and pharmaceutical compositions containing same

The subject of the invention is tricyclic derivatives of pyrazolecarboxylic acid of formula: in which R1 represents a C3-C15 carboxyl radical or an NR2R3 group. The invention also relates to the method for preparing the compounds of formula (I), pharmaceutical compositions containing them. The compounds of formula (I) are active on cannabinoid CB1 receptors.