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7-Chloro-1,3-dihydro-5-(2-methylphenyl)-2H-1,4-benzodiazepine-2-one is a complex organic chemical compound belonging to the benzodiazepine class. It is characterized by a benzene ring fused to a diazepine ring, with a chlorine atom at the 7th position, a 2-methylphenyl group at the 5th position, and a carbonyl group at the 2nd position. 7-Chloro-1,3-dihydro-5-(2-methylphenyl)-2H-1,4-benzodiazepine-2-one is known for its potential pharmacological properties, particularly as a tranquilizer or sedative. It is structurally similar to other benzodiazepines, which are widely used in medicine for their anxiolytic, anticonvulsant, muscle relaxant, and hypnotic effects. The specific substitution pattern in 7-Chloro-1,3-dihydro-5-(2-methylphenyl)-2H-1,4-benzodiazepine-2-one may confer unique properties or activities, although further research would be required to determine its exact therapeutic potential and safety profile.

5358-35-0

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5358-35-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5358-35-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,5 and 8 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5358-35:
(6*5)+(5*3)+(4*5)+(3*8)+(2*3)+(1*5)=100
100 % 10 = 0
So 5358-35-0 is a valid CAS Registry Number.

5358-35-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-chloro-5-(2-methylphenyl)-1,3-dihydro-1,4-benzodiazepin-2-one

1.2 Other means of identification

Product number -
Other names 7-chloro-5-o-tolyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5358-35-0 SDS

5358-35-0Relevant academic research and scientific papers

REACTION OF 4-CHLORO-1-NITROBENZENE WITH o-SUBSTITUTED PHENYLACETONITRILES; SYNTHESIS OF 8-CHLORO-1-METHYL(AND METHYLTHIOMETHYL)-6-(2-SUBSTITUTED PHENYL)-4H-s-TRIAZOLO-1,4-BENZODIAZEPINES

Vejdelek, Zdenek,Holubek, Jiri,Ryska, Miroslav,Koruna, Ivan,Svatek, Emil,et.al.

, p. 2545 - 2563 (2007/10/02)

Reactions of 4-chloro-1-nitrobenzene with 2-methyl-, 2-methoxy- and 2-(methylthio)phenylacetonitrile in methanolic potassium hydroxide gave mixture from which the excepted 3-aryl-5-chloro-2,1-benzisoxazoles Ia-c were isolated in addition to the 2H-indoles IIIa and IIIc and acridines VIII and IX.The 2,1-benzisoxazoles were reduced to the 2-aminobenzophenones XIIa-c which were transformed via the phthalimidoacetamido compounds XIIIa-c to 5-aryl-7-chloro-1,3-dihydro-1,4-benzodiazepine-2-ones XVa-c.Treatment with phosphorus pentasulfide led to the thiones XVIa-c which reacted in boiling butanol either with acetohydrazide or with (methylthio)acetohydrazide to give the title compounds XVIIa-c and XVIIIa-c.They showed only weak anticonvulsant, incoordinating and central depressant effects.

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