535920-91-3Relevant academic research and scientific papers
The surprising nucleophilic addition of aminochlorocarbenes to diethyl acetylenedicarboxylate and to oxalyl chloride: Quinolines and benzo[1,4]diazepines from N-alkylformanilides and oxalyl chloride in the presence of Huenig's base
Cheng, Ying,Yang, Hua,Meth-Cohn, Otto
, p. 3605 - 3610 (2007/10/03)
Vilsmeier reagents derived from N-methylformanilides undergo ready deprotonation with Huenig's base. In xylene, the derived nucleophilic arylaminochlorocarbenes bearing 4-methyl- and 4-methoxy-substituents react with acetylenedicarboxylates to give 2-(2-c
The unique nucleophilic reactivity of arylaminochlorocarbenes
Cheng, Ying,Yang, Hua,Meth-Cohn, Otto
, p. 90 - 91 (2007/10/03)
4-Methyl and 4-methoxyphenylaminochlorocarbene (readily formed by deprotonation of the Vilsmeier reagent derived from the corresponding N-methylformanilide with Huenig's base) reacted with diethyl acetylenedicarboxylate to give 1:2 quinoline adducts, whil
