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1-(Phenylsulfonyl)indole-3-sulfonyl chloride is a chemical compound with the molecular formula C16H10ClNO4S2. It is a sulfonyl chloride derivative of indole, a heterocyclic organic compound. This versatile reagent is widely used in organic synthesis for the functionalization of indole derivatives and other aromatic compounds. It also serves as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and functional materials, making it a valuable building block in the development of new drugs and materials with diverse applications in the pharmaceutical and agrochemical industries. Furthermore, it is an important reagent in medicinal chemistry and chemical biology research.

535930-73-5

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535930-73-5 Usage

Uses

Used in Organic Synthesis:
1-(Phenylsulfonyl)indole-3-sulfonyl chloride is used as a reagent for the functionalization of indole derivatives and other aromatic compounds, enabling the creation of a wide range of chemical products.
Used in Pharmaceutical Industry:
1-(Phenylsulfonyl)indole-3-sulfonyl chloride is used as a key intermediate in the synthesis of various pharmaceuticals, contributing to the development of new drugs with diverse therapeutic applications.
Used in Agrochemical Industry:
1-(Phenylsulfonyl)indole-3-sulfonyl chloride is used as a key intermediate in the synthesis of agrochemicals, aiding in the development of new products for agricultural applications.
Used in Functional Materials:
1-(Phenylsulfonyl)indole-3-sulfonyl chloride is used as a building block in the development of functional materials with various applications, such as in electronics, coatings, and other industries.
Used in Medicinal Chemistry Research:
1-(Phenylsulfonyl)indole-3-sulfonyl chloride is used as an important reagent in medicinal chemistry research, facilitating the discovery and optimization of new drug candidates.
Used in Chemical Biology Research:
1-(Phenylsulfonyl)indole-3-sulfonyl chloride is used as a reagent in chemical biology research, enabling the study of biological processes and the development of new probes and tools for understanding complex biological systems.

Check Digit Verification of cas no

The CAS Registry Mumber 535930-73-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,5,9,3 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 535930-73:
(8*5)+(7*3)+(6*5)+(5*9)+(4*3)+(3*0)+(2*7)+(1*3)=165
165 % 10 = 5
So 535930-73-5 is a valid CAS Registry Number.
InChI:InChI=1/C14H10ClNO4S2/c15-21(17,18)14-10-16(13-9-5-4-8-12(13)14)22(19,20)11-6-2-1-3-7-11/h1-10H

535930-73-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(Phenylsulfonyl)indole-3-sulfonyl chloride

1.2 Other means of identification

Product number -
Other names 1-(benzenesulfonyl)indole-3-sulfonyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:535930-73-5 SDS

535930-73-5Upstream product

535930-73-5Relevant academic research and scientific papers

Novel furanylarylene arylsulfonylindolesulfonamides: Synthesis and their antibacterial evaluation

Ramalingan, Chennan,Lee, In-Sook,Kwak, Young-Woo

experimental part, p. 591 - 596 (2009/12/27)

An array of furanylarylene arylsulfonylindolesulfonamides was synthesized through multi-step synthetic protocols involving bromination, stannylation, Stille cross coupling, reduction, arylsulfonylation, chlorosulfonylation, and condensation reactions. As

Efficient sulfonation of 1-phenylsulfonyl-1H-pyrroles and 1-phenylsulfonyl-1H-indoles using chlorosulfonic acid in acetonitrile

Janosik, Tomasz,Shirani, Hamid,Wahlstr?m, Niklas,Malky, Ilham,Stensland, Birgitta,Bergman, Jan

, p. 1699 - 1707 (2007/10/03)

The sulfonation of various 1-phenylsulfonyl-1H-pyrroles and 1-phenylsulfonyl-1H-indoles using chlorosulfonic acid in acetonitrile has been studied, leading to the development of a clean and operationally simple protocol allowing direct synthesis of the corresponding 1-phenylsulfonyl-1H-pyrrole-3- sulfonyl chlorides and 1-phenylsulfonyl-1H-indole-3-sulfonyl chlorides, respectively, both of which may be easily converted to various sulfonamide derivatives by treatment with nitrogen nucleophiles. Efficient and selective removal of the phenylsulfonyl- or tosyl groups in the sulfonamide series may be achieved under mild conditions.

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