53598-05-3Relevant academic research and scientific papers
Sodium tetraborate-dibenzo-18-crown ether-6 complex as reagent in the synthesis of cinnamic acids from aromatic aldehydes and aliphatic carboxylic acids
Chiriac, Constantin I.,Tanasa, Fulga,Nechifor, Marioara
experimental part, p. 419 - 423 (2012/01/03)
Cinnamic acids have been prepared in 74-81% yields by a new synthesis from aromatic aldehydes and aliphatic carboxylic acids in the presence of anhydrous sodium tetraborate-dibenzo-18-crown ether-6 complex as reagent, 4-dimethylaminopyridine as activating agent, pyridine as base, and N-methyl-2-pyrolidinone as solvent, at reflux (180-190°C) for 10-12 hours.
A novel approach in cinnamic acid synthesis: Direct synthesis of cinnamic acids from aromatic aldehydes and aliphatic carboxylic acids in the presence of boron tribromide
Chiriac, Constantin I.,Tanasa, Fulga,Onciu, Marioara
, p. 481 - 487 (2007/10/03)
Cinnamic acids have been prepared in moderate to high yields by a new direct synthesis using aromatic aldehydes and aliphatic carboxylic acids, in the presence of boron tribromide as reagent, 4-dimethylaminopyridine (4-DMAP) and pyridine (Py) as bases and N-methyl-2-pyrolidinone (NMP) as solvent, at reflux (180-190°C) for 8-12 hours.
New boron reagents for designed organic synthesis. 2 cinnamic acids synthesis in the presence of sodium tetramethoxyborate-lithium chloride
Chiriac, Constantin I.,Tanasǎ, Fulga,Onciu, Marioara
, p. 627 - 631 (2007/10/03)
Cinnamic acids were prepared in good to high yields by Perkin reaction between aromatic aldehydes and aliphatic anhydrides in the presence of a boron compound, namely sodium tetramethoxyborate-lithium chloride, as a novel catalyst for this synthesis and N-methyl-pyrrolidin-2-one (NMP) as a solvent, at reflux (170-180°C) for 9-12 hours.
A new direct synthesis of cinnamic acids from aromatic aldehydes and aliphatic carboxylic acids in the presence of sodium borohydride
Chiriac, Constantin I.,Tanasa, Fulga,Onciu, Marioara
, p. 3579 - 3580 (2007/10/03)
Cinnamic acids have been prepared in 59-86% yields by a new direct synthesis from aromatic aldehydes and aliphatic carboxylic acids in the presence of sodium borohydride and N-methyl-2-pyrrolidinone (NMP) as solvent, at reflux (185-190°C), for 9-12 hours. Without sodium borohydride, this reaction is not possible.
