43136-84-1

Basic information

• Product Name: Benzene, 1-chloro-3-(1-propyn-1-yl)-
• Synonyms: Benzene, 1-chloro-3-(1-propyn-1-yl)-
• CAS NO: 43136-84-1
• Molecular Formula: C₉H₇Cl
• Molecular Weight: 150.60488
• Mol File: 43136-84-1.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 226.7±23.0 °C(Predicted)
• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzene, 1-chloro-3-(1-propyn-1-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-chloro-3-(1-propyn-1-yl)-(43136-84-1)
• EPA Substance Registry System: Benzene, 1-chloro-3-(1-propyn-1-yl)-(43136-84-1)

Safety Data

• Hazardous Substances Data: 43136-84-1(Hazardous Substances Data)

Usage

General Description

Benzene, 1-chloro-3-(1-propyn-1-yl)- is a chemical compound with a molecular formula C9H7Cl. It is a chloroalkyne derivative of benzene, with a chlorine atom attached to the third carbon and a propynyl group attached to the first carbon of the benzene ring. Benzene, 1-chloro-3-(1-propyn-1-yl)- is used in various organic synthesis reactions and as a building block for the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as an intermediate in the synthesis of other compounds, including those used in the manufacturing of pesticides and herbicides. Benzene, 1-chloro-3-(1-propyn-1-yl)- is considered to be a hazardous chemical and should be handled with care due to its potential health and environmental hazards.

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Relevant articles and documents

Regio- And stereoselective electrochemical synthesis of sulfonylated enethers from alkynes and sulfonyl hydrazides

An electrooxidative direct difunctionalization of internal alkynes with sulfonyl hydrazides has been developed for the construction of sulfonated enethers. In this transformation, metal catalysts or stoichiometric amount of oxidants are not required and molecular nitrogen and hydrogen are the sole byproducts, providing a simple and green approach for preparing various sulfonyl tetrasubstituted alkenes. Notably, the protocol could be efficiently scaled up and the follow-up procedures of the corresponding functionalized alkenes demonstrate the practicality of the electrochemical synthesis.

A Convenient Procedure for Sonogashira Reactions Using Propyne

A modified Sonogashira coupling of aryl iodides and propyne was achieved using only two equivalents of propyne in THF from 78 °C to room temperature.

Direct Synthesis of 1-Arylprop-1-ynes with Calcium Carbide as an Acetylene Source

A simple method is described for the synthesis of 1-arylprop-1-ynes directly from aromatic aldehyde p -tosylhydrazones by using calcium carbide as an acetylene source. The salient features of this protocol are its use of a readily available and easily handled source of acetylene, its operational simplicity, its high yield, and its broad substrate scope.