53646-89-2Relevant articles and documents
Manganese-Catalyzed Multicomponent Synthesis of Pyrroles through Acceptorless Dehydrogenation Hydrogen Autotransfer Catalysis: Experiment and Computation
Borghs, Jannik C.,Azofra, Luis Miguel,Biberger, Tobias,Linnenberg, Oliver,Cavallo, Luigi,Rueping, Magnus,El-Sepelgy, Osama
, p. 3083 - 3088 (2019/01/09)
A new base metal catalyzed sustainable multicomponent synthesis of pyrroles from readily available substrates is reported. The developed protocol utilizes an air- and moisture-stable catalyst system and enables the replacement of themutagenic α-haloketones with readily abundant 1,2-diols. Moreover, the presented method is catalytic in base and the sole byproducts of this transformation are water and hydrogen gas. Experimental and computational mechanistic studies indicate that the reaction takes place through a combined acceptorless dehydrogenation hydrogen autotransfer methodology.
Selective ruthenium-catalyzed three-component synthesis of pyrroles
Zhang, Min,Neumann, Helfried,Beller, Matthias
supporting information, p. 597 - 601 (2013/02/23)
It's a snap: A novel catalytic three-component coupling reaction using simple and easily available substrates leads to a wide range of substituted pyrroles with high regioselectively (see scheme; Xantphos=9,9-dimethyl-4,5- bis(diphenylphosphino)xanthene). Copyright
Synthesis of 3-Phenylpyrroles by Hydride Reduction of 4-Hydroxypyrrolidin-2-ones
Hasegawa, Tadashi,Nakamura, Fuki,Moribe, Jun-ichi,Yoshioka, Michikazu
, p. 829 - 831 (2007/10/02)
3-Phenylpyrroles 2 were easily prepared in good yields by hydride reduction of 4-hydroxypyrrolidin-2-ones 1, which have been prepared in high yields from the photoreaction of N,N-dialkylbenzoylacetamides, with lithium aluminium hydride.
