53661-36-2Relevant academic research and scientific papers
Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase
Van Linden, Oscar P.J.,Farenc, Carine,Zoutman, Willem H.,Hameetman, Liesbeth,Wijtmans, Maikel,Leurs, Rob,Tensen, Cornelis P.,Siegal, Gregg,De Esch, Iwan J.P.
, p. 493 - 500 (2012/03/11)
The in silico identification, optimization and crystallographic characterization of a 6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c]isoquinolin-1-amine scaffold as an inhibitor for the EPHA4 receptor tyrosine kinase is described. A database containing commercially
EPHA4 RTK INHIBITORS FOR TREATMENT OF NEUROLOGICAL AND NEURODEGENERATIVE DISORDERS AND CANCER
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Page/Page column 37, (2010/05/13)
The present invention is directed to compounds of generic formula (I) which are inhibitors of ephrin A4. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatm
Studies on Fused 2(1H)-Pyridenethiones: New Routes for the Synthesis of Fused 1H-Pyrazolopyridines and Fused Thienopyridines
Al-Kaabi, Sharifa Soltan,Elgemeie, Galal Eldin Hamza
, p. 2241 - 2245 (2007/10/02)
A synthesis of fused 1H-pyrazolopyridines and fused thienopyridines utilizing fused 2(1H)-pyridinethiones as starting components is described.The structures of the products were assigned and confirmed on the basis of their elemental analysis
Studies on fused 2(1H)-pyridenethiones: New routes for the synthesis of fused 1H-pyrazolo[3,4-b]pyridines and fused thieno[2,3-b]pyridines
Al-Kaabi, Sharifa Soltan,Elgemeie, Galal Eldin Hamza
, p. 2241 - 2245 (2017/03/31)
A synthesis of fused 1H-pyrazolo[3,4-b]pyridines and fused thieno[2,3-b]pyridines utilizing fused 2(1H)-pyridinethiones as starting components is described. The structures of the products were assigned and confirmed on the basis of their elemental analysi
