38968-76-2

Usage

Uses

Used in Pharmaceutical Synthesis:
2-(4-Chlorobenzoyl)cyclohexanone is used as a building block in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and chemical compounds.
Used in Organic Synthesis:
As a ketone derivative, 2-(4-chlorobenzoyl)cyclohexanone is utilized in organic synthesis for the creation of diverse chemical compounds, expanding the scope of chemical research and applications.
Used in Antitumor Applications:
2-(4-Chlorobenzoyl)cyclohexanone exhibits antitumor properties, making it a subject of interest for potential medical applications. It may be further researched and developed as a therapeutic agent for cancer treatment.
Used in Antimicrobial Applications:
Due to its antimicrobial properties, 2-(4-chlorobenzoyl)cyclohexanone can be explored for use in the development of antimicrobial agents, potentially contributing to the fight against infectious diseases and antibiotic resistance.

Upstream product

• 108-94-1 cyclohexanone 
• 122-01-0 4-chloro-benzoyl chloride 
• 13161-16-5 2-[(4-Chloro-phenyl)-hydroxy-methyl]-cyclohexanone 
• 930-68-7 cyclohexenone 
• 873-76-7 para-Chlorobenzyl alcohol 
• 74-11-3 para-chlorobenzoic acid 

Downstream Products

• 42427-55-4 2-bromo-6-(4-chloro-benzoyl)-cyclohexanone 
• 144296-23-1 5-(4-chlorophenyl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c]isoquinolin-1-amine 
• 53661-36-2 3-chloro-1-(4-chlorophenyl)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile 
• 53661-30-6 1-(4-chlorophenyl)-3-hydroxy-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile 
• 61054-28-2 3-(4-chlorophenyl)-4,5,6,7-tetrahydrobenzisoxazole 

Relevant academic research and scientific papers

Iridium-catalyzed reaction of enones with alcohols affording 1,3-diketones

An iridium-catalyzed coupling reaction of alcohols with enones has been successfully developed providing access to 1,3-diketones with high selectivity in good yields. This reaction provides an atom-economical route to 1,3-diketones from readily available

Regiochemistry of the condensation of 2-aroyl-cyclohexanones and 2-cyanoacetamide: 13C-labeling studies and semiempirical MO calculations

Hydroxy-aryl-5,6,7,8-tetrahydroisoquinoline-4-carbonitriles represent interesting chemical scaffolds, but synthetic access to these compounds is limited. The reaction of 2-aroyl-cyclohexanones with 2-cyanoacetamide and base in ethanol has been reported to

Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase

The in silico identification, optimization and crystallographic characterization of a 6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c]isoquinolin-1-amine scaffold as an inhibitor for the EPHA4 receptor tyrosine kinase is described. A database containing commercially

High-yielding oxidation of β-hydroxyketones to β-diketones using o-Iodoxybenzoic acid

The oxidation of β-hydroxyketones to β-diketones was systematically investigated. o-Iodoxybenzoic acid (IBX) was found to be efficient, operationally easy, and superior to other common oxidants. The reaction is suitable for milligram- to gram-scale oxidations.

1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2

Novel 1,3-diarylcycloalkanopyrazoles 1, and diphenyl hydrazides 2 were identified as selective inhibitors of cyclooxygenase-2. The 1,3-diaryl substitution pattern of the pyrazole ring in 1 differentiates these compounds from most of the known selective COX-2 inhibitors that contain two aryl rings at the adjacent positions on a heterocyclic or a phenyl ring. Similarly, the two phenyl rings in 2 are also separated by three atoms. SAR of both phenyl rings in 1 and 2, and the aliphatic ring in 1 will be discussed. (C) 2000 Elsevier Science Ltd. All rights reserved.