53662-85-4

Basic information

• Product Name: Methyl tetrahydro-3-furoate
• Synonyms: Methyl tetrahydro-3-furoate;Methyl tetrahydrofuran-3-...;Methyl tetrahydrofuran-3-carboxylate;methyl oxolane-3-carboxylate
• CAS NO: 53662-85-4
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 130.1418
• Mol File: 53662-85-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 158.753 °C at 760 mmHg
• Flash Point: 55.161 °C
• Appearance: /
• Density: 1.109 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl tetrahydro-3-furoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl tetrahydro-3-furoate(53662-85-4)
• EPA Substance Registry System: Methyl tetrahydro-3-furoate(53662-85-4)

Safety Data

• Hazardous Substances Data: 53662-85-4(Hazardous Substances Data)

Usage

General Description

Methyl tetrahydro-3-furoate is an organic compound that is commonly used as a flavoring agent and fragrance ingredient. It is a colorless liquid with a fruity odor and is naturally found in fruits such as pineapple and strawberries. Methyl tetrahydro-3-furoate is often used in the food and beverage industry to enhance the aroma and flavor of products. It is also used in the production of perfumes, soaps, and other consumer products to give them a sweet and pleasant scent. Additionally, it has been studied for its potential antioxidant and antimicrobial properties, making it a versatile and useful chemical in various industries.

Upstream product

• 53750-81-5 4,5-dihydro-furan-3-carboxylic acid methyl ester 
• 865-33-8 potassium methanolate 
• 124391-75-9 3-tetrahydrofuranmethanol 
• 67-56-1 methanol 
• 89364-31-8 3-tetrahydrofuroic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 5204-91-1 methyl 5-oxotetrahydro-3-furancarboxylate 
• 1186609-16-4 5-(tetrahydrofuran-3-yl)-1H-pyrazol-3-amine 
• 1186610-03-6 3-oxo-3-(tetrahydro-furan-3-yl)-propionitrile 

Relevant articles and documents

Oxidative esterification of alcohols by a single-side organically decorated Anderson-type chrome-based catalyst

The direct esterification of alcohols with non-noble metal-based catalytic systems faces great challenges. Here, we report a new chrome-based catalyst stabilized by a single pentaerythritol decorated Anderson-type polyoxometalate, [N(C4H9)4]3[CrMo6O18(OH)3C{(OCH2)3CH2OH}], which can realize the efficient transformation from alcohols to esters by H2O2oxidation in good yields and high selectivity without extra organic ligands. A variety of alcohols with different functionalities including some natural products and pharmaceutical intermediates are tolerated in this system. The chrome-based catalyst can be recycled several times and still keep the original configuration and catalytic activity. We also propose a reasonable catalytic mechanism and prove the potential for industrial applications.

Conversion of alcohols to alkyl esters and carboxylic acids using heterogeneous palladium-based catalysts

Disclosed are methods for synthesizing an ester or a carboxylic acid from an organic alcohol. To form the ester one reacts, in the presence of oxygen gas, the alcohol with methanol or ethanol. This reaction occurs in the presence of a catalyst comprising palladium and a co-catalyst comprising bismuth, tellurium, lead, cerium, titanium, zinc and/or niobium (most preferably at least bismuth and tellurium). Alternatively that catalyst can be used to generate an acid from that alcohol, when water is also added to the reaction mix.

Aerobic oxidation of diverse primary alcohols to methyl esters with a readily accessible heterogeneous Pd/Bi/Te catalyst

Efficient aerobic oxidative methyl esterification of primary alcohols has been achieved with a heterogeneous catalyst consisting of 1 mol % Pd/charcoal (5 wt %) in combination with bismuth(III) nitrate and tellurium metal. The Bi and Te additives significantly increase the reaction rate, selectivity, and overall product yields. This readily accessible catalyst system exhibits a broad substrate scope and is effective with both activated (benzylic) and unactivated (aliphatic) alcohols bearing diverse functional groups.