53665-20-6

Usage

General Description

2,5-Pyrrolidinedione, 1-[(1-oxo-2-butenyl)oxy]-, also known as 1-(2-oxobut-1-en-1-yl)pyrrolidine-2,5-dione, is a chemical compound with the molecular formula C10H13NO3. It is a derivative of pyrrolidinedione and is commonly used as a substrate in organic synthesis. 2,5-Pyrrolidinedione, 1-[(1-oxo-2-butenyl)oxy]- is known to exhibit anti-inflammatory and analgesic properties and has potential applications in the pharmaceutical industry for the development of new drugs. Additionally, it is used in the manufacturing of various products such as adhesives, coatings, and polymers. Overall, the compound has versatile chemical properties and has potential applications in several industries.

Upstream product

• 3724-65-0 2-butenoic acid 
• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 

Downstream Products

• 1399861-03-0 ε-N-crotonyl lysine 

Relevant academic research and scientific papers

Application of chiral ligands: Carbohydrates, nucleoside-lanthanides and other Lewis acid complexes to control regio- and stereoselectivity of the dipolar cycloaddition reactions of nitrile oxides and esters

Chiral Lewis acid mediated 1,3-dipolar cycloaddition reactions of 4-trifluoromethylbenzonitrile oxide to methyl crotonate as well to β-substituted acrylates and (Z)-pent-2-en-1-yl esters were examined. Excellent enantioselectivities with moderate to good regioselectivities were achieved for crotonates with complexes of BiBr3 with (+)-(4,6-benzylidene)methyl-α-d-glucopyranoside C, with the l-ascorbic acid I-FeCl3 system, and with lipase Candida antarctica. High enantiomeric excess was observed for isopropyl ester and benzyl ester. The outstanding ee values were achieved for acrylates with β-t-butyl, cyclohexyl, and 1,3-benzodioxol-5-yl groups in cycloadditions catalyzed by C-Yb(OTf)3 and the (+)-2-hydroxy-3-pinanone N-TiCl4 system. High enantioselectivities were found in reactions of (Z)-pent-2-en-1-yl esters mediated by complexes N-Mg(OTf)2 and N-TiCl4.