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536760-29-9

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  • 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

    Cas No: 536760-29-9

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536760-29-9 Usage

Chemical Properties

Class white powder

Uses

3-?Chloro-?1-?(4-?nitrophenyl)?-?5,?6-?dihydropyridin-?2(1H)?-?one is used in the preparation of Apixaban intermediates and impurities.

Check Digit Verification of cas no

The CAS Registry Mumber 536760-29-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,6,7,6 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 536760-29:
(8*5)+(7*3)+(6*6)+(5*7)+(4*6)+(3*0)+(2*2)+(1*9)=169
169 % 10 = 9
So 536760-29-9 is a valid CAS Registry Number.
InChI:InChI=1S/C11H9ClN2O3/c12-10-2-1-7-13(11(10)15)8-3-5-9(6-4-8)14(16)17/h2-6H,1,7H2

536760-29-9Relevant articles and documents

Preparation method of apixaban and intermediates thereof

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, (2018/05/16)

The invention discloses a preparation method of apixaban and intermediates thereof. The invention provides a preparation method of an apixaban intermediate I. The preparation method of the apixaban intermediate I comprises the step of performing nucleophilic substitution reaction on an apixaban intermediate II and p-fluoronitrobenzene in an organic solvent in the presence of an alkali to obtain the apixaban intermediate I. The preparation method has short steps, simple and safe operation, simple post-treatment steps, environmental friendliness and high total yield, and the obtained product hashigh purity, low production cost and high atomic utilization, and is suitable for industrial production. The formula is shown in the description.

Process for preparing 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones

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Page/Page column 12-13, (2010/10/20)

A novel process and intermediates thereof for making 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones of the type shown below from appropriate phenyl hydrazines is described. These compounds can be useful as factor Xa inhibitors.

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