5368-32-1 Usage
Uses
Used in Pharmaceutical Industry:
(R)-N-4-Benzyl-2-phenylpiperazine is used as a precursor in the synthesis of various drugs for its ability to contribute to the development of new therapeutic agents.
Used in Drug Discovery and Development:
(R)-N-4-Benzyl-2-phenylpiperazine is utilized as a valuable tool in drug discovery and development due to its unique structure and pharmacological properties, which can be leveraged to create innovative treatments.
Used in Neurological Disorder Treatment:
(R)-N-4-Benzyl-2-phenylpiperazine is being investigated for its potential use in the treatment of various neurological disorders, showcasing its promise as a therapeutic agent for such conditions.
While the provided materials do not specify the exact neurological disorders or the reasons for its use in treatment, the general application in the treatment of neurological disorders is based on its potential as a therapeutic agent and its investigation in this area. Further research and development would be necessary to determine the specific applications and reasons for its use in treating particular neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 5368-32-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,6 and 8 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 5368-32:
(6*5)+(5*3)+(4*6)+(3*8)+(2*3)+(1*2)=101
101 % 10 = 1
So 5368-32-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H20N2/c1-3-7-15(8-4-1)13-19-12-11-18-17(14-19)16-9-5-2-6-10-16/h1-10,17-18H,11-14H2
5368-32-1Relevant academic research and scientific papers
Visible-Light-Driven CarboxyLic Amine Protocol (CLAP) for the Synthesis of 2-Substituted Piperazines under Batch and Flow Conditions
Gueret, Robin,Pelinski, Lydie,Bousquet, Till,Sauthier, Mathieu,Ferey, Vincent,Bigot, Antony
, p. 5157 - 5162 (2020/07/14)
Piperazines are privileged scaffolds in medicinal chemistry. Disclosed herein is a visible-light-promoted decarboxylative annulation protocol between a glycine-based diamine and various aldehydes to access 2-aryl, 2-heteroaryl, as well as 2-alkyl piperazines. The iridium-based complex [Ir(ppy)2(dtbpy)]PF6 and carbazolyl dicyanobenzene 4CzIPN were found to be the photocatalysts of choice to efficiently perform the transformation under mild conditions, whether in batch or in continuous mode.
Biocatalytic Access to Piperazines from Diamines and Dicarbonyls
Borlinghaus, Niels,Gergel, Sebastian,Nestl, Bettina M.
, p. 3727 - 3732 (2018/04/14)
Given the widespread importance of piperazines as building blocks for the production of pharmaceuticals, an efficient and selective synthesis is highly desirable. Here we show the direct synthesis of piperazines from 1,2-dicarbonyl and 1,2-diamine substrates using the R-selective imine reductase from Myxococcus stipitatus as biocatalyst. Various N- and C-substituted piperazines with high activity and excellent enantioselectivity were obtained under mild reaction conditions reaching up to 8.1 g per liter.
