5371-55-1

Basic information

• Product Name: (1E)-1,3-diphenylpropan-1-one oxime
• CAS NO: 5371-55-1
• Molecular Formula: C₁₅H₁₅NO
• Molecular Weight: 225.2857
• Mol File: 5371-55-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 389.7°C at 760 mmHg
• Flash Point: 248.9°C
• Density: 1.02g/cm³
• Vapor Pressure: 9.02E-07mmHg at 25°C
• Refractive Index: 1.556
• CAS DataBase Reference: (1E)-1,3-diphenylpropan-1-one oxime(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-1,3-diphenylpropan-1-one oxime(5371-55-1)
• EPA Substance Registry System: (1E)-1,3-diphenylpropan-1-one oxime(5371-55-1)

Safety Data

• Hazardous Substances Data: 5371-55-1(Hazardous Substances Data)

Usage

General Description

The chemical (1E)-1,3-diphenylpropan-1-one oxime, also known as Benzophenone oxime, is an organic compound with the molecular formula C15H13NO. It is a ketoxime derivative of benzophenone, commonly used as a photoinitiator in the production of plastics and adhesives. It acts as a radical scavenger, helping to prevent the degradation of polymers due to exposure to light. Additionally, it exhibits antioxidant properties and can be employed as a stabilizer in the formulation of rubber and other industrial materials. Its various applications make it a valuable chemical in the manufacturing and processing of diverse materials.

Upstream product

• 1083-30-3 dihydrochalcone 
• 61608-94-4 1-(2-(phenylmethyl)phenyl)ethanone 
• 4894-23-9 3,5-diphenyl-4,5-dihydro-isoxazole 
• 6738-06-3 phenylethynylmagnesium bromide 
• 1081-75-0 1,3-diphenylpropane 
• 4980-70-5 1,3-diphenyl-1-propyne 
• 4747-13-1 α-methoxystyrene 
• 108-88-3 toluene 

Downstream Products

• 71255-48-6 1,3-Diphenylpropylidenamino-oxyessigsaeure 
• 2039-49-8 3,5-diphehylisoxazole 
• 4894-23-9 3,5-diphenyl-4,5-dihydro-isoxazole 
• 21837-74-1 1,3-Diphenyl-1-propanone azine 
• 151475-94-4 1,3-diphenyl-1-(2,3-epoxypropyloximino)propane 

Relevant articles and documents

TEMPO-Mediated Selective Synthesis of Isoxazolines, 5-Hydroxy-2-isoxazolines, and Isoxazoles via Aliphatic δ-C(sp3)-H Bond Oxidation of Oximes

Selective synthesis of three different bioactive heterocycles; isoxazolines, 5-hydroxy-2-isoxazolines and isoxazoles from the same starting material using TEMPO (2,2,6,6-Tetramethylpiperidin-1-oxyl) as a radical initiator is reported. Selectivity was achi

Copper-Catalyzed Aza-Sonogashira Cross-Coupling To Form Ynimines: Development and Application to the Synthesis of Heterocycles

Nitrogen-substituted alkynes, such as ynamines and ynamides, are versatile synthetic building blocks. Ynimines bearing additional nucleophilic and electrophilic centers relative to ynamines and ynamides are expected to have high synthetic potential. However, their chemical reactivity remains unexplored owing mainly to the lack of synthetic accessibility. We report herein a versatile copper-catalyzed synthesis of ynimines from readily available O-acetyl ketoximes and terminal alkynes. A wide range of O-acetyl ketoximes derived from diaryl ketones, aryl alkyl ketones and dialkyl ketones underwent cross-coupling with a diverse set of terminal alkynes to afford the ynimines in good to excellent yields. An unprecedented [5+1] heteroannulation reaction exploiting the reactivity of the ynimine generated in situ was subsequently developed for the synthesis of medicinally important heterocycles, including isoquinolines, azaindoles, azabenzofurans, azabenzothiophenes and carbolines.

Copper-Catalyzed Asymmetric Addition of Tertiary Carbon Nucleophiles to 2 H-Azirines: Access to Chiral Aziridines with Vicinal Tetrasubstituted Stereocenters

A catalytic asymmetric nucleophilic addition of tertiary carbon nucleophiles to 2H-azirines was established in the presence of the chiral N,N′-dioxide/CuII complex. Various chiral aziridines with vicinal tetrasubstituted stereocenters were obta