53710-41-1Relevant articles and documents
Palladium-catalyzed arylation of allylic diols: Highly selective synthesis of phenyl-substituted allylic diols
Kang, Suk-Ku,Jung, Kyung-Yun,Park, Chan-Hee,Namkoong, Eun-Young,Kim, Tae-Hyun
, p. 6287 - 6290 (1995)
The coupling reaction of iodobenzene with allylic diols in the presence of Pd(OAc)2 and nBu3P as catalysts using K2CO3 as base afforded the phenyl-substituted allylic diols. However, under the same reaction conditions with Et3N as base, phenyl-substituted α-hydroxy ketone was obtained.
Nickel-Catalyzed Highly Selective Hydroalkenylation of Alkenyl Boronic Esters to Access Allyl Boron
Zhang, Penglin,Zhang, Min,Ji, Yuqi,Xing, Mimi,Zhao, Qian,Zhang, Chun
supporting information, p. 8285 - 8290 (2020/11/12)
Allyl boron derivatives are valuable building blocks in the synthesis of natural products and bioactive molecules. Herein, a practical strategy of nickel-catalyzed highly selective hydroalkenylation of alkenyl boronic esters was developed. Under the mild
Ni-Catalyzed regio- and stereoselective addition of arylboronic acids to terminal alkynes with a directing group tether
Hari Babu, Madala,Ranjith Kumar, Gadi,Kant, Ruchir,Sridhar Reddy, Maddi
, p. 3894 - 3897 (2017/04/04)
Addition of arylboronic acids to directing group tethered acetylenes in a regio and stereoselective manner using an inexpensive catalytic system is achieved for the first time to access highly sought after allyl/homoallyl alcohol/amine units. The apparent vinylnickel intermediate was successfully trapped by the Michael electrophiles to get defined tri- and tetra-substituted olefins. An interesting selectivity switch was observed with internal alkynes.
Tandem Benzylic Oxidation/Dihydroxylation of α-Vinyl- and α-Alkenylbenzyl Alcohols
Fernandes, Rodney A.,Kattanguru, Pullaiah
, p. 92 - 107 (2015/10/19)
A de novo tandem benzylic oxidative dihydroxylation of α-vinyl- and α-alkenylbenzyl alcohols has been developed to give α,β-dihydroxypropiophenones (=2,3-dihydroxy-1-phenylpropan-1-ones) and α,β-dihydroxyalkyl phenones. This method was shown to be substrate-selective and specific for the oxidation of benzylic alcohols.
Highly selective 1,3-isomerization of allylic alcohols via rhenium oxo catalysis
Morrill, Christie,Grubbs, Robert H.
, p. 2842 - 2843 (2007/10/03)
Two reaction strategies are developed to promote the highly selective 1,3-isomerization of a variety of allylic alcohols using O3ReOSiPh3 as a catalyst. The first strategy utilizes substrates whose 1,3-regioisomer contains a conjugated alkene, which relies on thermodynamics to obtain high selectivity. The second strategy employs N,O-bis(trimethylsilyl)acetamide as an additive to selectively and irreversibly remove the product from the reaction equilibrium and works well for the isomerization of tertiary allylic alcohols into primary allylic alcohols containing trisubstituted alkene components. High stereoselectivity is also observed in the 1,3-isomerization of enantioenriched allylic alcohols. Copyright
