53772-20-6

Basic information

• Product Name: 1-benzyloxy-3-methylnaphthalen-4-yl acetate
• Synonyms: 1-benzyloxy-3-methylnaphthalen-4-yl acetate
• CAS NO: 53772-20-6
• Molecular Weight: 306.361
• Mol File: 53772-20-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyloxy-3-methylnaphthalen-4-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyloxy-3-methylnaphthalen-4-yl acetate(53772-20-6)
• EPA Substance Registry System: 1-benzyloxy-3-methylnaphthalen-4-yl acetate(53772-20-6)

Safety Data

• Hazardous Substances Data: 53772-20-6(Hazardous Substances Data)

Upstream product

• 573-20-6 menadiol di(acetate) 
• 2211-27-0 4-acetoxy-3-methyl-1-naphthol 
• 100-39-0 benzyl bromide 

Downstream Products

• 916432-92-3 1-(1-benzyloxy-3-methylnaphthalen-4-yloxy)propan-2-one 
• 53772-22-8 4-Benzyloxy-1-methoxy-2-methyl-naphthalene 
• 53772-21-7 2-methyl-4-benzyloxy-1-naphthol 

Relevant articles and documents

Synthesis and cytotoxicity of 9-substituted benzo[de]chromene-7,8-dione and 5-benzyl-9-substituted benzo[de]chromene-7,8-dione

New Mansonone analogues of 9-substitued benzo[de]chromene-7,8-dione 5b-e and 5-benzyl-9-substitued benzo[de]chromene-7,8-dione 6a-e were prepared through a modified route. The first step involved a bulky base t-butylamine mediated regioselective deacetylation of 2-substituted-1,4-naphth-diyl diacetate, resulting in obtaining of monoacetate 4-acetate 2 in high yield. The mechanism of cyclization, debenzylation, and oxidation for the formation of 5a-e and 6a-e were discussed. The cytotoxicity of the prepared compounds 5 and 6 were comparable with naturally occurring Mansonone F. Copyright Taylor & Francis Group, LLC.