53779-78-5

Basic information

• Product Name: 2-Buten-1-one, 4,4,4-trichloro-1-phenyl-, (2E)-
• CAS NO: 53779-78-5
• Molecular Formula: C10H7Cl3O
• Molecular Weight: 249.524
• Mol File: 53779-78-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Buten-1-one, 4,4,4-trichloro-1-phenyl-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Buten-1-one, 4,4,4-trichloro-1-phenyl-, (2E)-(53779-78-5)
• EPA Substance Registry System: 2-Buten-1-one, 4,4,4-trichloro-1-phenyl-, (2E)-(53779-78-5)

Safety Data

• Hazardous Substances Data: 53779-78-5(Hazardous Substances Data)

Upstream product

• 75-87-6 chloral 
• 93-91-4 1-phenylbutan-1,3-dione 
• 98-86-2 acetophenone 
• 13505-41-4 4,4,4-trichloro-3-hydroxy-1-phenylbutan-1-one 

Downstream Products

• 807331-42-6 4,4-dichloro-1-phenylbut-3-en-1-one 
• 53810-71-2 Phenyl-((1R,2R,3R,4S)-3-trichloromethyl-bicyclo[2.2.1]hept-5-en-2-yl)-methanone 

Relevant articles and documents

First synthesis of 1-aryl-4,4-dichlorobut-3-en-1-ones. The electrochemical reduction of 1-aryl-4,4,4-trichlorobut-2-en-1-ones as a key step

The first method for the synthesis of 1-aryl-4,4-dichlorobut-3-en-1-ones is reported. Treatment of acetophenones with anhydrous chloral leads to 1-aryl-4,4,4-trichloro-3-hydroxybutan-1-ones in near quantitative yields. These compounds were efficiently deh

A convenient synthesis of olefins via deacylation reaction

A convenient and environmentally-friendly synthetic method of olefins via deacylation reaction is described. The reaction gives olefins by condensation of aldehydes with a variety of 1,3-dicarbonyl compounds in the presence of anhydrous potassium carbonate at room temperature in high yields (70-90%) in one step. The synthetic potential of this strategy can be used as an alternative procedure to the Wittig, Wittig-Horner reactions. The stereochemistry of the resulted olefins was determined by NOE experiment with correct radio frequency and X-ray analysis. The E/Z selectivity of the deacylation reaction depends on the α-substituents of the 1,3-dicarbonyl compounds.