53779-84-3

Basic information

• Product Name: 2,4-DIIODO-1,3,5-TRIMETHYL-BENZENE
• Synonyms: 2,4-DIIODO-1,3,5-TRIMETHYL-BENZENE;VITAS-BB TBB000524
• CAS NO: 53779-84-3
• Molecular Formula: C₉H₁₀I₂
• Molecular Weight: 371.98
• Mol File: 53779-84-3.mol
• Article Data: 22

Chemical Properties

• Melting Point: 82-83 °C(Solv: ethanol (64-17-5))
• Boiling Point: 322.8±37.0 °C(Predicted)
• Appearance: /
• Density: 2.039±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2,4-DIIODO-1,3,5-TRIMETHYL-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIIODO-1,3,5-TRIMETHYL-BENZENE(53779-84-3)
• EPA Substance Registry System: 2,4-DIIODO-1,3,5-TRIMETHYL-BENZENE(53779-84-3)

Safety Data

• Hazardous Substances Data: 53779-84-3(Hazardous Substances Data)

Usage

General Description

2,4-Diiodo-1,3,5-trimethylbenzene is a chemical compound with the molecular formula C9H9I2. It is a derivative of benzene with three methyl groups and two iodine atoms attached to the benzene ring. 2,4-DIIODO-1,3,5-TRIMETHYL-BENZENE is commonly used in organic synthesis and as a reagent in chemical reactions. It is also used as a building block in the production of various pharmaceuticals, agrochemicals, and other specialty chemicals. 2,4-Diiodo-1,3,5-trimethylbenzene may pose health and environmental risks, and proper safety precautions should be taken when handling this chemical.

Upstream product

• 4028-63-1 iodomesitylene 
• 108-67-8 1,3,5-trimethyl-benzene 
• 7446-11-9 sulfur trioxide 
• 3453-83-6 mesitylene sulfonic acid 

Downstream Products

• 19025-36-6 2,4,6-triiodomesitylene 
• 38329-18-9 1,3-diiodo-2,4,6-trimethyl-5-nitro-benzene 
• 1042414-02-7 2,4-bis(4-bromophenylthio)-1,3,5-trimethylbenzene 

Relevant articles and documents

R4NHal/NOHSO4: A Usable System for Halogenation of Isoxazoles, Pyrazoles, and beyond

A new convenient and versatile halogenating system (R4NHal/NOHSO4), giving straightforward and general access to halogenated 3,5-diaryl- and alkylarylisoxazoles, pyrazoles and electron-rich benzenes from the corresponding scaffolds, is suggested. The method provides excellent regioselectivity, scalability to the gram scale, and a broad scope for both aromatics and halogens. A three-step, one-pot reaction protocol was developed, and a series of 3,5-diaryl-4-haloisoxazoles has been efficiently synthesized from 1,2-diarylcyclopropanes under suggested nitrosating-halogenating conditions.

Metal-Free, Oxidant-Free, and Controllable Graphene Oxide Catalyzed Direct Iodination of Arenes and Ketones

A direct, metal-free, and oxidant-free method for the graphene oxide (GO)-catalyzed iodination of arenes and ketones with iodine in a neutral medium was explored. This iodination protocol was performed by using a simple technique to avoid the use of external metal catalysts and oxidants and harsh acidic/basic reaction conditions. In addition, by this method the degree of iodination could be controlled, and the reaction was scalable and compatible with air. This strategy opens a new field for GO-catalyzed chemistry and provides an avenue for the convenient direct iodination of arenes and ketones.

Electrophilic aryl-halogenation using N-halosuccinimides under ball-milling

We report here a methodology of chemo- and regio-selective aryl bromination and iodination using respective N-halosuccinimides at room temperature in the absence of any solvents, catalyst/additives under ball-milling condition. However, for chlorination ceric ammonium nitrate was used as additive. The coupled product succinimide, produced from the reactions, was recycled via regeneration of NBS. This methodology works with the electron-donor substituted or unsubstituted arenes.