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2-(N-benzoyl)-amino-5-phenyl-[1,3,4]oxadiazole is a complex organic compound with the molecular formula C15H10N2O2. It is a derivative of the [1,3,4]oxadiazole ring system, which is a five-membered heterocyclic compound containing two nitrogen atoms and one oxygen atom. The molecule features a benzoyl group (C6H5-CO-) attached to the nitrogen atom at position 2, and a phenyl group (C6H5-) at position 5. 2-(N-benzoyl)-amino-5-phenyl-[1,3,4]oxadiazole is known for its potential applications in the field of pharmaceuticals and materials science, particularly as a building block for the synthesis of various biologically active molecules and functional materials. Its unique structure and properties make it an interesting target for further research and development in these areas.

5378-59-6

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5378-59-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5378-59-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,7 and 8 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5378-59:
(6*5)+(5*3)+(4*7)+(3*8)+(2*5)+(1*9)=116
116 % 10 = 6
So 5378-59-6 is a valid CAS Registry Number.

5378-59-6Relevant academic research and scientific papers

Highly efficient green phosphorescent organic light-emitting diodes with low efficiency roll-off based on iridium(III) complexes bearing oxadiazol-substituted amide ligands

Zhang, Fuli,Li, Weiling,Yu, Yue,Jing, Yiming,Ma, Dongxin,Zhang, Fuqiang,Li, Suzhi,Cao, Guangxiu,Li, Zhongyi,Guo, Ge,Wei, Bin,Zhang, Depan,Duan, Lian,Li, Chunyang,Feng, Yafei,Zhai, Bin

, p. 5469 - 5475 (2016)

Two novel iridium(iii) complexes [Ir(ppy)2(PhOXD)] (1, ppy = 2-phenylpyridine, PhOXD = N-(5-phenyl-1,3,4-oxadiazol-2-yl)-benzamide) and [Ir(ppy)2(POXD)] (2, POXD = N-(5-phenyl-1,3,4-oxadiazol-2-yl)-diphenylphosphinic amide) have been

Design and evaluation of novel oxadiazole derivatives as potential prostate cancer agents

Mochona, Bereket,Qi, Xin,Euynni, Suresh,Sikazwi, Donald,Mateeva, Nelly,Soliman, Karam F.

, p. 2847 - 2851 (2016)

Various 1,3,4-oxadiazole derivatives have been synthesized and their antiproliferative properties have been studied. The in vitro screening was performed against androgen dependent (LNCaP) and androgen independent (PC-3) prostate cancer cell lines. Most o

A useful synthesis of 2-acylamino-1,3,4-oxadiazoles from acylthiosemicarbazides using potassium iodate and the discovery of new antibacterial compounds

Li, Tianlei,Wen, Gang,Li, Jishun,Zhang, Wenxuan,Wu, Song

, (2019/05/02)

A useful method for the synthesis of 2-acylamino-1,3,4-oxadiazoles was developed. By using potassium iodate as an oxidant in water at 60 ?C, a wide range of 2-acylamino-1,3,4-oxadiazoles were afforded in moderate to excellent yields within two

Oxadiazole imide such green light iridium complex and its preparation method and application

-

Paragraph 0022; 0025, (2017/08/25)

The invention discloses an oxadiazole imide green iridium complex which is bis[2-phenylpyridine]-{2-(N-benzoyl)-amino-5-phenyl-[1,3,4]-oxadiazole) complex iridium A or bis[2-phenylpyridine]-{2-(N-biphenyl phosphonate)-amino-phenyl-[1,3,4]-oxadiazole) comp

A Highly Efficient Diversification of 2-Amino/Amido-1,3,4-oxadiazole and 1,3,4-Thiadiazole Derivatives via Reagent-Based Cyclization of Thiosemicarbazide Intermediate on Solid-Phase

Yang, Seung-Ju,Choe, Ji-Hye,Abdildinova, Aizhan,Gong, Young-Dae

, p. 732 - 741 (2015/12/23)

A 2-amino/amido-1,3,4-oxadiazole and 1,3,4-thiadiazole library has been constructed on solid-phase organic synthesis. The key step on this solid-phase synthesis involves the preparation of polymer-bound 2-amino-1,3,4-oxadiazole and 1,3,4-thiadiazole core

Experimental and DFT studies on competitive heterocyclic rearrangements. Part 2: A one-atom side-chain versus the classic three-atom side-chain (Boulton-Katritzky) ring rearrangement of 3-acylamino-1,2,4-oxadiazoles

Pace, Andrea,Pibiri, Ivana,Piccionello, Antonio Palumbo,Buscemi, Silvestre,Vivona, Nicolo,Barone, Giampaolo

, p. 7656 - 7666 (2008/02/12)

(Chemical Equation Presented) The experimental investigation of the base-catalyzed rearrangements of 3-acylamino-1,2,4-oxadiazoles evidenced a new reaction pathway which competes with the well-known ring-degenerate Boulton-Katritzky rearrangement (BKR). T

New access to pyrazole, oxa(thia)diazole and oxadiazine derivatives

Hassan, Alaa A.,El-Shaieb, Kamal M.,Shaker, Raafat M.,Doepp, Dietrich

, p. 12 - 19 (2007/10/03)

1,4-Disubstituted thiosemicarbazides 1b-f reacted with ethenetetracarbonitrile (5) in dimethylformamide with formation of 2-substituted 5-phenyl-1,3,4-thiadiazoles 2a-f and 2-substituted 5-phenyl-1,3,4-oxadiazoles 4a-f. Upon addition of 5 to 1c-e in chlorobenzene, 3-amino-2-benzoyl-4,5,5- tricyano-2,5-dihydro-1H-pyrazole- 1-[N-(4-tricyanovinyl)phenyl]carbothioamide (12), 5-benzylamino-, and 5-allylamino-4-benzoyl-2,3-dihydro-[1,3,4]thiadiazol- 2,2-dicarbonitrile (13a,b) and 5-amino-1-benzoylpyrazole-3,4-dicarbonitrile (14) as well as 2-phenyl-4H-[1,3,4]-oxadiazine-5,6-dicarbonitrile (15) were formed. Rationales for the role of the solvent and the conversions observed are presented.

DUAL REACTIVITY OF 2-AMINO-5-ARYL-1,3,4-OXADIAZOLES

Alekseeva, V. Ya.,Vergizov, S. N.,Dymshits, V. A.,Viktorovskii, I. V.,V'yunov, K. A.

, p. 2002 - 2007 (2007/10/02)

The benzoylation of 2-amino-5-aryl-1,3,4-oxadiazoles in aprotic and protic solvents was investigated.It was shown that the formation of two isomeric products (2-benzoylamino-5-aryl-1,3,4-oxadiazoles and 3-benzoyl-2-imino-5-aryl-1,3,4-oxadiazoles possible

NOVEL REARRANGEMENT OF 3-ACYL-5-ACYLAMINO-2,3-DIHYDRO-1,3,4-THIADIAZOLE 1-OXIDE INTO 1,3,4-OXADIAZOLES

Kubota, Seiju,Toyooka, Kouhei,Yamamoto, Naoya,Kasai, Takayuki,Shibuya, Masayuki

, p. 21 - 24 (2007/10/02)

Thermally, or in the presence of p-toluenesulfonic acid, 3-acyl-5-acylamino-2,3-dihydro-1,3,4-thiadiazole 1-oxides are transformed into 1,3,4-oxadiazoles, carbonyl compounds and sulfur.

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