53780-24-8Relevant academic research and scientific papers
A new approach to 3-substituted indoles through palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamines
Inamoto, Kiyofumi,Saito, Tadataka,Hiroya, Kou,Doi, Takayuki
experimental part, p. 3157 - 3162 (2009/06/18)
Palladium-catalyzed C-H activation followed by intramolecular amination reaction of enamine compounds was achieved using a Pd(OAc)2 (10 mol%)/Cu(OAc)2 (100 mol%) catalyst system in DMSO. This work introduces an entirely new approach to 3-substituted indoles. Georg Thieme Verlag Stuttgart.
ACID AND ESTER COMPOUNDS AND METHODS OF USING THE SAME
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Page/Page column 35; 61, (2008/06/13)
Disclosed is a compound of having the formula (II-A), pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solvates of this invention are useful as LXR agonists.
Synthesis and structure-activity relationship studies of novel 2-diarylethyl substituted (2-carboxycycloprop-1-yl)glycines as high-affinity group II metabotropic glutamate receptor ligands.
Sorensen, Ulrik S,Bleisch, Thomas J,Kingston, Anne E,Wright, Rebecca A,Johnson, Bryan G,Schoepp, Darryle D,Ornstein, Paul L
, p. 197 - 205 (2007/10/03)
The major excitatory neurotransmitter in the central nervous system, (S)-glutamic acid , activates both ionotropic and metabotropic excitatory amino acid receptors. Its importance in connection to neurological and psychiatric disorders has directed great
Diphenylpropylamines
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, (2008/06/13)
1,1-DIPHENYL-2-HYDROXY-3-AMINOPROPANE DERIVATIVES ARE USEFUL FOR THEIR PSYCHOTROPIC ACTIVITY AND, IN PARTICULAR ARE USEFUL AS ANTIDEPRESSANTS.
