5382-77-4

Basic information

• Product Name: diethyl tetrahydropyran-4,4-dicarboxylate
• Synonyms: diethyl tetrahydropyran-4,4-dicarboxylate;4H-Pyran-4,4-dicarboxylic acid, tetrahydro-, 4,4-diethyl ester;DIETHYL DIHYDRO-2H-PYRAN-4,4(3H)-DICARBOXYLATE
• CAS NO: 5382-77-4
• Molecular Formula: C11H17O5-
• Molecular Weight: 229.24968
• Mol File: 5382-77-4.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 275.2°Cat760mmHg
• Flash Point: 114.7°C
• Appearance: /
• Density: 1.127g/cm³
• Vapor Pressure: 0.00518mmHg at 25°C
• Refractive Index: 1.458
• CAS DataBase Reference: diethyl tetrahydropyran-4,4-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl tetrahydropyran-4,4-dicarboxylate(5382-77-4)
• EPA Substance Registry System: diethyl tetrahydropyran-4,4-dicarboxylate(5382-77-4)

Safety Data

• Hazardous Substances Data: 5382-77-4(Hazardous Substances Data)

Usage

General Description

Diethyl tetrahydropyran-4,4-dicarboxylate is an organic compound classified as an ester. As an ester, it is derived from an acid (in this case, tetrahydropyran-4,4-dicarboxylic acid) and an alcohol (in this case, ethanol). This chemical is notable for its six-membered cyclic structure. The tetrahydropyran ring in its structure places it among the class of heterocyclic compounds, which contain atoms of at least two different elements in their rings. Applications or uses of diethyl tetrahydropyran-4,4-dicarboxylate can vary but tend to be in the field of organic chemistry for synthetic applications. The specific properties, reactivities, and safety issues related to this chemical would depend on its precise physical and chemical characteristics.

InChI:InChI=1/C11H18O5/c1-3-15-9(12)11(10(13)16-4-2)5-7-14-8-6-11/h3-8H2,1-2H3

Upstream product

• 111-44-4 3-oxa-1,5-dichloropentane 
• 105-53-3 diethyl malonate 
• 34270-90-1 2,2'-diiodoethyl ether 
• 6986-48-7 bis-1-chloroethyl ether 

Downstream Products

• 5337-04-2 tetrahydro-4H-pyran-4,4-dicarboxylic acid 
• 108630-68-8 4-(ethoxycarbonyl)tetrahydro-2H-pyran-4-carboxylic acid 
• 96835-17-5 ethyl tetrahydro-2H-pyran-4-carboxylate 
• 89975-77-9 (tetrahydro-2H-pyran-4,4-diyl)dimethanol 
• 128094-82-6 tetrahydro-thiopyran-4-carboxylic acid methyl ester 
• 100277-27-8 (tetrahydro-2H-thiopyran-4-yl)methanol 
• 195503-55-0 (1-Methyl-1-{4-[1-methyl-1-(methyl-phenyl-carbamoyl)-ethylcarbamoyl]-tetrahydro-pyran-4-ylcarbamoyl}-ethyl)-carbamic acid benzyl ester 
• 195503-53-8 {1-Methyl-1-[4-(methyl-phenyl-carbamoyl)-tetrahydro-pyran-4-ylcarbamoyl]-ethyl}-carbamic acid benzyl ester 
• 195503-54-9 4-(2-Benzyloxycarbonylamino-2-methyl-propionylamino)-tetrahydro-pyran-4-carboxylic acid 
• 195503-45-8 N-methyl-N-phenyl-6-oxa-1-azaspiro[2.5]oct-1-en-2-amine 
• 26170-23-0 tetrahydro-N-methyl-N-phenyl-2H-pyran-4-carboxamide 
• 40191-32-0 tetrahydro-2H-pyran-4-carbonylchloride 
• 5337-03-1 tetrahydro-2H-pyran-4-carboxylic acid 

Relevant articles and documents

A process for preparing 4, 4 - pyran dicarboxylic acid diethyl ester derivative method

The invention relates to a method for preparing 4,4-pyran diethyl dicarboxylate and a derivative thereof. According to the invention, diethyl malonate and substituted dichloroethyl ether are adopted as raw materials; cuprous iodide is used for catalyzing; one or a mixture of compounds selected from potassium tert-butoxide, sodium tert-butoxide and sodium tert-pentoxide is adopted as an alkali, and a reaction is carried out; when the reaction is finished, a solvent is removed by reduced-pressure distillation; and reduced-pressure distillation is continued, such that 4,4-pyran diethyl dicarboxylate or the derivative thereof are obtained. The method provided by the invention has never been reported before. The raw materials are easy to obtain, the reaction method is simple and feasible, and the reaction time is short. The method has high application and market values.

2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS

The invention provides compounds of formula (I), and pharmaceutically acceptable salts thereof wherein: Rl, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. These compounds are useful in the manufacture of medicaments for use in the prevention or treatment of a fungal disease. Compounds of formula (I), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.

Processes for preparing 3-Arylsulfur hydroxamic acids

This invention provides processes for the preparation of a compound of Formula I: Y—C(═O—C(R1)(R2)—CH2—S(O)nR3 wherein: Y is hydroxy or XONX, where each X is independently hydrogen, lower alkyl or lower acyl; R1is hydrogen or lower alkyl; R2is hydrogen, lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, or R1and R2together with the carbon atom to which they are attached form a cycloalkyl or heterocyclo group; R3is aryl; and n is 0, 1 or 2. The invention also provides novel aryl haloalkyl sulfide intermediates useful for the preparation of compounds of Formula I and novel methods of preparing aryl alkyl sulfides.