538372-35-9

Upstream product

• 13138-78-8 1-methyl-4-nitro-pyrrol-2-carboxylic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 538372-33-7 5,6-diamino-pyridine-2-carboxylic acid methyl ester 
• 84487-04-7 6-bromo-3-nitro-pyridin-2-ylamine 
• 538372-32-6 6-amino-5-nitro-pyridine-2-carboxylic acid methyl ester 
• 273-21-2 1H-Imidazo[4,5-b]pyridine 

Downstream Products

• 538372-36-0 2-(4-tert-butoxycarbonylamino-1-methyl-1H-pyrrole-2-yl)-3H-imidazo[4,5-b]pyridine-5-carboxylic acid 

Relevant academic research and scientific papers

Imidazopyridine/pyrrole and hydroxybenzimidazole/pyrrole pairs for DNA minor groove recognition

The DNA binding properties of fused heterocycles imidazo[4,5-b]pyridine (Ip) and hydroxybenzimidazole (Hz) paired with pyrrole (Py) in eight-ring hairpin polyamides are reported. The recognition profile of Ip/Py and Hz/Py pairs were compared to the five-m

Alternative heterocycles for DNA recognition

Methods and compositions are provided for forming complexes between dsDNA and novel oligomers comprising fused six-membered rings. By appropriate choice of target sequences and oligomers, complexes comprising oligomer-DNA are obtained with high association constants. The formation of complexes can be used for identification of specific dsDNA sequences, for inhibiting gene transcription, and as a therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific genes.