538372-33-7

Usage

Uses

Used in Pharmaceutical Industry:
2-Pyridinecarboxylic acid, 5,6-diamino, methylester (9CI) is used as an intermediate in the synthesis of pharmaceuticals for its potential as a drug candidate for the treatment of various diseases. Its biological activities, such as antimicrobial, antifungal, and antitumor properties, make it a subject of interest for pharmaceutical research and development.
Used in Agrochemical Industry:
2-Pyridinecarboxylic acid, 5,6-diamino, methylester (9CI) is used as an intermediate in the synthesis of agrochemicals, where its antimicrobial and antifungal properties can be utilized for the development of effective pesticides and other agricultural products.
Used in Food and Agricultural Sciences:
2-Pyridinecarboxylic acid, 5,6-diamino, methylester (9CI) has potential applications in the fields of food and agricultural sciences, where its biological activities can be employed for various purposes, such as enhancing food safety or improving crop protection.

Upstream product

• 84487-06-9 6-amino-5-nitropyridine-2-carboxylic acid 
• 84487-04-7 6-bromo-3-nitro-pyridin-2-ylamine 
• 21901-29-1 6-amino-5-nitro-2-picoline 
• 538372-32-6 6-amino-5-nitro-pyridine-2-carboxylic acid methyl ester 

Downstream Products

• 538372-35-9 2-(4-tert-butoxycarbonylamino-1-methyl-1H-pyrrole-2-yl)-3H-imidazo[4,5-b]pyridine-5-carboxylic acid methyl ester 
• 538372-36-0 2-(4-tert-butoxycarbonylamino-1-methyl-1H-pyrrole-2-yl)-3H-imidazo[4,5-b]pyridine-5-carboxylic acid 

Relevant academic research and scientific papers

BICYCLIC HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF MAMMALIAN HISTONE DEACETYLASE ACTIVITY

A compound of formula (Ia) or (Ib) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of a histone deacetylase, and as such is useful in terepy, e.g. in the treatment of autoimmune disorders, mental disorders, neurodegenerative disorders, and hyperproliferative disorders.

Lithium Hexamethyldisilazane Transformation of Transiently Protected 4-Aza/Benzimidazole Nitriles to Amidines and their Dimethyl Sulfoxide Mediated Imidazole Ring Formation

Trimethylsilyl-transient protection successfully allowed the use of lithium hexamethyldisilazane to prepare benzimidazole (BI) and 4-azabenzimidazole (azaBI) amidines from nitriles in 58-88% yields. This strategy offers a much better choice to prepare BI/azaBI amidines than the lengthy, low-yielding Pinner reaction. Synthesis of aza/benzimidazole rings from aromatic diamines and aldehydes was affected in dimethyl sulfoxide in 10-15 min, while known procedures require long time and purification. These methods are important for the BI/azaBI-based drug industry and for developing specific DNA binders for expanded therapeutic applications.

FUSED TRIAZOLE DERIVATIVES AS PHOSPHODIESTERASE 10A INHIBITORS

Compounds of the general formula (I), wherein one of X1 and X2 represents N, and the other one of X1 and X2 represents -C(CH3), A represents unsubstituted or substituted 5-, 6-or 10-membered aryl or h

Synthesis and inhibitory activity of benzoic acid and pyridine derivatives on influenza neuraminidase

Based upon the activity and X-ray crystallographic studies of tri-substituted benzene derivatives containing carboxylic acid, acetamido and guanidine groups, we investigated the effect of the fourth substituent to fulfill the fourth pocket of neuraminidas

Alternative heterocycles for DNA recognition

Methods and compositions are provided for forming complexes between dsDNA and novel oligomers comprising fused six-membered rings. By appropriate choice of target sequences and oligomers, complexes comprising oligomer-DNA are obtained with high association constants. The formation of complexes can be used for identification of specific dsDNA sequences, for inhibiting gene transcription, and as a therapeutic for inhibiting proliferation of undesired cells or modulation of expression of specific genes.

Imidazopyridine/pyrrole and hydroxybenzimidazole/pyrrole pairs for DNA minor groove recognition

The DNA binding properties of fused heterocycles imidazo[4,5-b]pyridine (Ip) and hydroxybenzimidazole (Hz) paired with pyrrole (Py) in eight-ring hairpin polyamides are reported. The recognition profile of Ip/Py and Hz/Py pairs were compared to the five-m