53872-43-8

Basic information

• Product Name: dimethyl 2-benzamidomalonate
• Synonyms: dimethyl 2-benzamidomalonate
• CAS NO: 53872-43-8
• Molecular Weight: 251.239
• Mol File: 53872-43-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: dimethyl 2-benzamidomalonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-benzamidomalonate(53872-43-8)
• EPA Substance Registry System: dimethyl 2-benzamidomalonate(53872-43-8)

Safety Data

• Hazardous Substances Data: 53872-43-8(Hazardous Substances Data)

Upstream product

• 6773-29-1 dimethyl diazomalonate 
• 55-21-0 benzamide 
• 108-59-8 malonic acid dimethyl ester 
• 16115-80-3 dimethyl aminomalonate hydrochloride 
• 98-88-4 benzoyl chloride 

Relevant articles and documents

Direct catalytic asymmetric synthesis of N-heterocycles from commodity acid chlorides by employing α,β-unsaturated acylammonium salts

Taming the beast, asymmetrically: Modulation of the reactivity of acid chlorides, using cinchona alkaloid catalysts, results in chiral α,β-unsaturated acylammoniums, which react with nucleophiles enantioselectively to give pyrrolidinones, piperid-2-ones,

New insertion reactions of some carbenoids into amide- and sulfonamide-NH bonds

In the presence of catalytic amounts of Rh2(OAc)4 in toluene, dimethyl diazomalonate (1) decomposed with evolution of N2 to form a carbenoid of type 8 which reacted with carboxamides 2 and toluenesulfonamide (4) to give 2-(acylamino)- and 2-(sulfonylamino)malonates 3 and 5, respectively. In an analogous reaction, α-diazo ketone 6 and 4 yielded N-(2-oxo-1,2-diphenylethyl)toluenesulfonamide (7).