53911-82-3Relevant articles and documents
Rhodium-catalyzed enamine homologation of sulfides with triazoles as carbene precursor
Li, Fang,Pei, Chao,Koenigs, Rene M.
, p. 6816 - 6821 (2020)
We report on Rh(II)-catalyzed enamine homologation reactions of triazoles with cyclopropylmethyl sulfides. This reaction proceeds via Dimroth rearrangement of triazoles followed by rhodium-catalyzed ylide formation. This ylide, however, does not undergo classic rearrangement reactions. Instead, it undergoes a selective, intramolecular alkylation reaction to yield cyclopropylmethyl-substituted enamides. The application of this reaction was evaluated with different triazoles and sulfides, which underline the special reactivity of cyclopropylmethyl sulfides (29 examples, up to 83% yield).
Mode of alkylation of alcohols with O-cyclopropylmethyl trichloroacetimidate and O-cyclobutyl trichloroacetimidate
Ali, Ibrahim A.I.,Zhu, Xiangming,El Ashry, El Sayed H.,Schmidta, Richard R.
experimental part, p. 35 - 44 (2012/03/09)
Acid promoted alkylation of hydroxy group containing acceptors 3-14 with O-cyclopropylmethyl and O-cyclobutyl trichloroacetimidates 1 and 2, respectively, afforded ethers with cyclopropylmethyl, cyclobutyl, and homoallyl residues as a result of the rearrangement of the cation intermediates. The dependence of product formation on acceptor structure is discussed. ARKAT-USA, Inc.
Surprisingly facile addition of thiols to the double bonds of bicyclopropylidene and other methylenecyclopropanes
Kozhushkov, Sergei I.,Brandl, Melanie,De Meijere, Armin
, p. 1535 - 1542 (2007/10/03)
The addition of thiols 8a-h onto the double bonds of bicyclopropylidene (1) and methylenespiropentane (2) proceeds quantitatively in benzene at 20 to 75 °C in the absence of catalysts or radical initiators to give products 9, 10 with complete retention of
