10437-85-1

Basic information

• Product Name: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER
• Synonyms: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER;Cyclobutanol, 1-(4-Methylbenzenesulfonate);cyclobutyl 4-methylbenzenesulfonate
• CAS NO: 10437-85-1
• Molecular Formula: C₁₁H₁₄O₃S
• Molecular Weight: 226.29
• Mol File: 10437-85-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER(10437-85-1)
• EPA Substance Registry System: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER(10437-85-1)

Safety Data

• Hazardous Substances Data: 10437-85-1(Hazardous Substances Data)

Usage

General Description

Toluene-4-sulfonic acid cyclobutyl ester is a chemical compound composed of toluene-4-sulfonic acid and cyclobutyl ester. It is commonly used as a reagent in various chemical synthesis processes, particularly in the pharmaceutical and agrochemical industries. TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER is known for its ability to act as a strong acid catalyst and as a nucleophile in organic reactions. It is also used as a building block in the synthesis of a variety of pharmaceutical drugs and biologically active molecules. Toluene-4-sulfonic acid cyclobutyl ester is a versatile chemical that is widely utilized in the field of organic chemistry.

Upstream product

• 2919-23-5 cyclobutanol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 885267-05-0 (2-bromophenyl)(cyclobutyl)sulfane 
• 53911-82-3 (cyclopropylmethyl)(phenyl)sulfane 
• 67132-84-7 cyclobutyl phenyl sulfide 
• 4285-49-8 homoallyl phenyl sulfide 
• 144773-93-3 1,5-dibromocyclopentene 
• 86488-28-0 (+/-)-2-bromocyclopent-2-enol 
• 822-35-5 cyclobutene 
• 6861-61-6 cyclobutane thiol 

Relevant articles and documents

SUBSTITUTED OXOPYRIDINE DERIVATIVES

The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic

Compounds Having CRTH2 Antagonist Activity

Compounds of general formula (I) wherein W is chloro or fluoro; Z is a group SO2R1; wherein R1 is —C3-C8 cycloalkyl or heterocyclyl optionally substituted with one or more substituents chosen from hal

Dynamic models for the thermal deazetization of 2,3-diazabicyclo[2.2.1]hept-2-ene

Kinetic studies on the thermal nitrogen extrusion from 2,3-diazabicyclo[2.2.1]hept-2-ene-exo,exo-5,6-d2 are reported. The ratio of rate constants for formation of the label-isomeric products (bicyclo[2.1.0]pentane-exo,exo-2,3-d2 and -endo,endo-2,3-d2) is found to exhibit no statistically significant temperature dependence. A comparison of gas-phase and solution-phase results is presented. The results are interpreted in terms of two complementary dynamic models. In the first, classical trajectory calculations are run on a three-dimensional projection (two geometric coordinates) of the potential energy hypersurface. These calculations correctly identify the major product, and reproduce the near temperature-independence of the rate-constant ratio, but do not match the ratio quantitatively. Modification of the trajectory calculations to simulate the effect of collisions with solvent molecules also qualitatively matches the observed difference between gas-phase and solution-phase behavior. In the second model, the vector of atomic displacements corresponding to the reaction coordinate at the transition state for nitrogen loss is identified by both semiempirical and ab initio calculations. The components of this vector pointing along the paths to the post-transition-state minima are computed and are shown to lead to a prediction of the product ratio that is in good (if partly fortuitous) agreement with the experimental result. The vector model is used to predict isotope effects on the product ratio, which are then investigated experimantally with 2,3-diazabicyclo[2.2.1]hept-2-ene-endo,endo-1,4,5,6,7,7-d6 and -endo-7-d.