53941-18-7Relevant academic research and scientific papers
Efficient one-pot synthesis of substituted pyrazoles
Tang, Meng,Zhang, Fu-Min
, p. 1427 - 1433 (2013/02/25)
An efficient, one-pot synthesis of substituted pyrazoles from enones, hydrazides, and halides was developed. In comparison with the classical Knorr pyrazole synthesis, this methodology gave a different type of product (R 3≥R5). A range of substituted pyrazoles were prepared in good to high yields with complete regioselectivity.
A new 1,4-elimination of benzenesulfinic acid from β-keto phenylsulphones via their tosylhydrazones
Ballini, Roberto,Bosica, Giovanna,Marcantoni, Enrico
, p. 10705 - 10710 (2007/10/03)
Reaction of β-keto phenylsulphone tosylhydrazones 2 with 2 eq. of DBU, at r.t. in dichloromethane, affords α,β-unsaturated ketone tosylhydrazones 4, via the tosylazoalkenes 3 obtained by 1,4-elimination of benzenesulfinic acid.
The Photolysis of p-Tosylhydrazones of Aryl and α,β-Unsaturated Carbonyl Compounds
Bellesia, Franco,Grandi, Romano,Pagnoni, Ugo M.,Trave, Roberto
, p. 1301 - 1309 (2007/10/02)
The ultraviolet irradiation of p-tosylhydrazones of aryl and α,β-unsaturated carbonyl compounds yields azines and sulphones and exhibits a strong solvent effect.Styryl substrates afford α,β-unsaturated sulphones, the shift of the olefinic double bond probably arising through an intermediate azoderivative.The p-tosylhydrazone of benzylideneacetone is to a great extent transformed to the cis isomer.
