53951-44-3

Usage

Uses

Used in Chemical Synthesis:
2-Ethyl-1,3-dioxolane-4-methanol is used as a reagent in the selective ruthenium-mediated synthesis of mixed acetals and orthoesters. Its application is particularly relevant in the addition of alcohol and phenols to allyl ethers, where it serves as a key intermediate in the formation of these complex organic compounds. This reactivity and selectivity make it a valuable tool in the synthesis of a wide range of chemical products, including pharmaceuticals, agrochemicals, and specialty chemicals.

InChI:InChI=1/C6H12O3/c1-2-6-8-4-5(3-7)9-6/h5-7H,2-4H2,1H3

Upstream product

• 123-38-6 propionaldehyde 
• 56-81-5 glycerol 
• 123-34-2 3-allyloxy-1,2-propanediol 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 123-38-6 propionaldehyde 
• 56-81-5 glycerol 

Relevant academic research and scientific papers

Synthesis of dioxolanylmethyl methacrylates from aldehydes, glycerol, and methyl methacrylate

The feasibility of preparing dioxolanylmethyl methacrylates from aldehydes in two stages (without purification of intermediate 4-hydroxymethyl-1,3-dioxane) was examined.

Structure–Activity Relationships of WOx-Promoted TiO2–ZrO2 Solid Acid Catalyst for Acetalization and Ketalization of Glycerol towards Biofuel Additives

Abstract: WOx-promoted TiO2–ZrO2 solid acid catalyst was prepared and applied in the catalytic acetalization and ketalization of glycerol with carbonyl compounds to produce biofuel additives. The presence of WOx promoter and TiO2 remarkably improved the catalytic activity of ZrO2. Approximately, 100% glycerol conversion was evidenced with non-bulky aliphatic aldehydes and ketones like, propanol and cyclohexanone. The physical characterization of WOx-promoted TiO2–ZrO2, revealed a higher formation of tetragonal crystalline phase of ZrO2, over monoclinic. The total surface acidity and the ratio of Br?nsted to Lewis acidic site concentrations were determined by NH3-TPD and pyridine-chemisorbed FTIR spectroscopy, respectively. A considerably higher concentration of Lewis acidic sites, ~ 213.29?μmol/gm, was evidenced on the WOx-promoted TiO2–ZrO2 catalyst surface. Catalytic activity study revealed a direct correlation between the surface Lewis acidic site concentration and the activity of catalyst. This significant observation indicated the key role of Lewis acidic sites in this catalytic process. The WOx-promoted TiO2–ZrO2 catalyst was also considerably stable and showed good performance in the acetalization/ketalization of glycerol with other substituted carbonyl compounds. Graphic Abstract: The WOx-promoted TiO2–ZrO2 solid acid catalyst exhibits superior catalytic performance for acetalization and ketalization of glycerol with carbonyl compounds to produce biofuel additives. [Figure not available: see fulltext.].

A selective and convenient ruthenium mediated method for the synthesis of mixed acetals and orthoesters

Addition of alcohols and phenols to O-allyl compounds (allyl ethers and acrolein acetals), catalyzed by [RuCl2(PPh3)3], was examined. Intramolecular addition of an OH group, leading to the formation of cyclic acetals and o

Highly selective isomerization of allyloxyalcohols to cyclic acetals or 1-propenyloxyalcohols

Highly selective isomerization of allyloxyalcohols either to 1-propenyl derivatives or to cyclic acetals of propanal depending on the transition metal (Ru, Rh) complex used is described together with a proposed explanation of an alternative reaction, which permits broad application of the described method.

Features of synthesis of 4-hydroxymethyl-1,3-dioxolanes from glycerol and aldehydes

Specific features of reaction of glycerol with aldehydes, compared to ketones, were revealed, and formation of 4-hydroxymethyl-1,3-dioxolanes from glycerol and lower aldehydes (acetaldehyde, propionaldehyde, and butyraldehyde) was examined. The products were isolated, and their physicochemical characteristics were determined.