5398-76-5

Basic information

• Product Name: 2-(2-cyanophenyl)ethyl acetate
• CAS NO: 5398-76-5
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.2105
• Mol File: 5398-76-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 298.6°C at 760 mmHg
• Flash Point: 137.7°C
• Density: 1.11g/cm³
• Vapor Pressure: 0.00126mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: 2-(2-cyanophenyl)ethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-cyanophenyl)ethyl acetate(5398-76-5)
• EPA Substance Registry System: 2-(2-cyanophenyl)ethyl acetate(5398-76-5)

Safety Data

• Hazardous Substances Data: 5398-76-5(Hazardous Substances Data)

Usage

General Description

2-(2-cyanophenyl)ethyl acetate is a chemical compound with the molecular formula C11H11NO2. It is a colorless liquid that is used as a solvent and as a flavoring agent in food and beverages. This chemical is also known for its fruity odor and is used in the fragrance and flavor industry. It is synthesized through the esterification of 2-(2-cyanophenyl)ethanol with acetic acid. 2-(2-cyanophenyl)ethyl acetate has potential applications in various industries, including pharmaceuticals, cosmetics, and food manufacturing. Additionally, it is important to handle this chemical with caution as it may cause irritation to the skin and eyes upon contact.

Upstream product

• 5339-85-5 2-aminophenethyl alcohol 
• 42247-74-5 2-(2-hydroxyethyl)benzonitrile 
• 75-36-5 acetyl chloride 

Downstream Products

• 79536-84-8 (5-O-Tritylthymidin-3')(2-chlorphenyl)(2-cyano-4-nitrophenylaethyl)phosphorsaeureester 
• 79536-81-5 2-(2-Cyano-4-nitrophenyl)aethanol 

Relevant articles and documents

Nucleotide. XIV. Substituierte β-Phenylaethyl-Gruppen. Neue Schutzgruppen fuer Oligonucleotid-Synthesen nach dem Phosphorsaeuretriester-Verfahren

Various o- and p-substituted β-phenylethanols (2-10) have been synthesized and investigated as blocking groups in the phosphotriester approach.A large number of 5'-O-tritylated thymidine-3'-phosphotriesters (13-36) with two different phosphate protecting groups have been prepared, characterized, and studied according to their chemical stability and usefullness for oligonucleotide syntheses.The combination of a 5'-O-monomethoxytrityl- and a 3'-(2,5-dichlorophenyl, p-nitrophenylethyl)-phosphate function as in 18 turned out to possess optimal properties as a monomeric nucleotide building block due to the fact that these blocking groups can be quantitatively and selectively be removed without harming each other by trifluoroacetic acid in chloroform to 41, by oximate to 42, and by DBU to 43.The base-catalyzed removal of the monosubstituted phenylethyl groups by DBU or DBN respectively as well as the disubstituted phenylethyl groups by triethylamine in aprotic solvents is a β-elimination process leading to phosphodiesters without attack on the P-center.